As a result of investigation on architectonics of structural organization of the brain neocortex in dolphin, frontal, parietal, temporal and occipital regions, as well as certain fields were distinguished. Monotonous character and incomplete stratification of the neocortical lamina, lack of clear border line and similarity with interstitial formations demonstrate symbolic meaning of the word neocortex as it is applied to the cetacean brain. Therefore, the term preneocortex is suggested for the dolphin brain.
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Circ Genom Precis Med
January 2025
Centre for Heart Lung Innovation, University of British Columbia, Vancouver. (K.H., M.A., L.R., Y.L., A.S., H.H., L.R.B., Z.W.L.).
Background: Protein-truncating mutations in the titin gene are associated with increased risk of atrial fibrillation. However, little is known about the underlying pathophysiology.
Methods: We identified a heterozygous titin truncating variant (TTNtv) in a patient with unexplained early onset atrial fibrillation and normal ventricular function.
AoB Plants
January 2025
INRAE, URP3F, 86600 Lusignan, France.
Perennial grasses' reproductive phenology profoundly impacts plant morphogenesis, biomass production, and perenniality in natural ecosystems and cultivated grasslands. Complex interactions between vegetative and reproductive development complicate grass phenology prediction for various environments and genotypes. This work aims to analyse genetic × environment interactions effects on tiller growth and reproductive development in Three perennial ryegrass cultivars, Bronsyn, Carvalis, and Tryskal, were grown from seedling to heading under four inductive conditions.
View Article and Find Full Text PDFTzu Chi Med J
August 2024
Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Schizophrenia (SCZ) is a chronic psychotic disorder that profoundly alters an individual's perception of reality, resulting in abnormal behavior, cognitive deficits, thought distortions, and disorientation in emotions. Many complicated factors can lead to SCZ, and investigations are ongoing to understand the neurobiological underpinnings of this condition. Presynaptic Netrin G1 and its cognate partner postsynaptic Netrin-G-Ligand-1 (NGL-1) have been implicated in SCZ.
View Article and Find Full Text PDFInorg Chem
January 2025
CNRS, University of Bordeaux, Bordeaux INP, ICMCB UMR CNRS 5026, F-33600 Pessac ,France.
The diaspore-type crystalline structure is historically well-known in mineralogy, but it has also been widely studied for various applications in the field of catalysis, electrocatalysis, and batteries. However, once two anions of similar ionic size but different electronegativity, such as F and O or more precisely OH, are combined, the knowledge of the location of these two anions is of paramount importance to understand the chemical properties in relation with the generation of hydrogen bonds. Coprecipitation and hydrothermal routes were used to prepare hydroxide-fluorides that crystallize all in an orthorhombic structure with four formula units per cell.
View Article and Find Full Text PDFBiomark Res
January 2025
Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
The tumor microenvironment functions as a dynamic and intricate ecosystem, comprising a diverse array of cellular and non-cellular components that precisely orchestrate pivotal tumor behaviors, including invasion, metastasis, and drug resistance. While unraveling the intricate interplay between the tumor microenvironment and tumor behaviors represents a tremendous challenge, recent research illuminates a crucial biological phenomenon known as cellular mechanotransduction. Within the microenvironment, mechanical cues like tensile stress, shear stress, and stiffness play a pivotal role by activating mechanosensitive effectors such as PIEZO proteins, integrins, and Yes-associated protein.
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