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Cardiovascular problems in rabbits in reference to hypothyroidism - a four-year retrospective study.
Pol J Vet Sci
December 2024
Department of Epizootiology and the Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Głęboka 30, 20-612 Lublin, Poland.
The effects of T4 are mainly manifested by positive ino- and chronotropism. The syndrome accompanying hypothyroidism in rabbits (impaired myocardial contractility and reduced ejection capacity) is caused by a deficiency of thyroid hormones - especially T4. The study group consisted of a total of 41 animals: 15 males and 26 females, ranging in age from 2 months to 8 years, with echocardiogram showing reduced fractional shortening (<30%), with normal results of heamatological and biochemical tests.
View Article and Find Full Text PDFCarcinoembryonic Antigen Expression in Human Tumors: A Tissue Microarray Study on 13,725 Tumors.
Cancers (Basel)
December 2024
Institute of Pathology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Background/objectives: Carcinoembryonic antigen (CEA) is a cell-surface glycoprotein serving as a drug target, diagnostic marker, and serum marker for cancer monitoring. However, prevalence data on CEA expression in cancer tissues vary considerably. This study was designed to determine CEA expression in normal and neoplastic tissues.
View Article and Find Full Text PDF3D printed sodium alginate/gelatin/tannic acid/calcium chloride scaffolds laden bone marrow mesenchymal stem cells to repair defective thyroid cartilage plate.
J Biomater Appl
November 2024
Department of Otorhinolaryngology Head and Neck Surgery, Sichuan Taikang Hospital, Chengdu, China.
Due to the absence of blood vessels, cartilage exhibits extremely limited self-repair capacity. Currently, repairing laryngeal cartilage defects, resulting from conditions such as laryngeal tumors, injury, and congenital structural abnormalities, remains a significant challenge in the Department of Otolaryngology, Head and Neck Surgery. Previous research has often focused on enhancing the mechanical properties of synthetic materials.
View Article and Find Full Text PDFMitigating intubation stress, mucosa injury, and inflammatory response in nasogastric tube intubation suppression of the NF-κB signaling pathway by engineering a hydration lubrication coating.
J Mater Chem B
October 2024
West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu 610041, China.
Nasogastric tube (NGT) intubation is a common yet critical clinical procedure. However, complications arising from tube friction result in awful pain and morbidity. Here, we report a straightforward surface modification of slender NGT utilizing highly hydrated micelles that were composed of hyaluronic acid and Pluronic.
View Article and Find Full Text PDFPancreatic inflammation induced by hypothyroidism in female rabbits is associated with cholesterol accumulation and a reduced expression of CYP51A1, FXRβ, and PPARβ/δ.
Anat Rec (Hoboken)
October 2024
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico.
In women and animal models, hypothyroidism induces hypercholesterolemia, pancreatitis, and insulitis. We investigated whether lipids are involved in the effects of hypothyroidism in the pancreas. Control (n = 6) and hypothyroid (n = 6) adult female rabbits were used.
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