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Computational modeling of neuromuscular activation by transcutaneous electrical nerve stimulation to the lower back.
Biomed Phys Eng Express
March 2025
Biomedical Engineering Department, The City College of New York, 160 Convent Ave, New York, 10031-9101, UNITED STATES.
Objectives Transcutaneous Electrical Nerve Stimulation (TENS) to the lower back is an established electrical therapy for acute and chronic back pain. The efficacy and mechanisms of lower back TENS depend on the penetration depth of electrical current. We compare the intensity and spatial extent (depth) of current flow in the body during TENS with varied electrode positions/shapes on the human back.
View Article and Find Full Text PDFRegional anesthesia for arrhythmias: a review of current literature.
Curr Opin Anaesthesiol
February 2025
Department of Anesthesiology and Perioperative Medicine; University of Texas Medical Branch, Galveston, Texas, USA.
Purpose Of The Review: The aim is to provide a comprehensive review of regional anesthesia techniques to control ventricular arrhythmias.
Recent Findings: While promising, the use of stellate ganglion block (SGB) for arrhythmia control is still under investigation, and further clinical trials are warranted to fully understand its efficacy, long-term outcomes, suitable patient group, and safety profile. Nevertheless, it remains a potential adjunctive therapy in the management of ventricular arrhythmias in select patients.
Comparative effect of nonpharmacological interventions on emergence delirium prevention in children following sevoflurane general anesthesia: A systematic review and network meta-analysis of randomized controlled trials.
Int J Nurs Stud
February 2025
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; Department of Nursing, Taipei Medical University Hospital, Taipei, Taiwan; Research Center of Sleep Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Research Center of Sleep Medicine, Taipei Medical University Hospital, Taipei, Taiwan. Electronic address:
Background: Children receiving general anesthesia while undergoing surgery have a significantly high incidence of emergence delirium (ED). Nonpharmacological interventions yield beneficial effects on preventing pediatric ED. However, the relative effects of nonpharmacological interventions on pediatric ED prevention based on various perioperative phases remain unknown.
View Article and Find Full Text PDFIndividualized PEEP can improve both pulmonary hemodynamics and lung function in acute lung injury.
Crit Care
March 2025
Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.
Rationale: There are several approaches to select the optimal positive end-expiratory pressure (PEEP), resulting in different PEEP levels. The impact of different PEEP settings may extend beyond respiratory mechanics, affecting pulmonary hemodynamics.
Objectives: To compare PEEP levels obtained with three titration strategies-(i) highest respiratory system compliance (C), (ii) electrical impedance tomography (EIT) crossing point; (iii) positive end-expiratory transpulmonary pressure (P)-in terms of regional respiratory mechanics and pulmonary hemodynamics.
Impact of L-thyroxine on hippocampal activity, morphology, and behavioral performance in thyroidectomized rats.
Metab Brain Dis
March 2025
Histochemistry and Morphology Lab, Orbeli Institute of Physiology NAS RA, Yerevan, 0028, Armenia.
Thyroid hormones, particularly L-thyroxine, are integral to cognitive processes like learning and memory. However, electrophysiological and morphological evidence connecting thyroid hormone activity to hippocampal function remains limited. This study aims to investigate the electrophysiological, morphological, and behavioral effects of L-thyroxine treatment in thyroidectomized (TX) rats, addressing the complex interplay between thyroid hormone regulation and hippocampal function.
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