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Sleeve gastrectomy improves HDL function examined by Apo-A1 and atherogenic indices in non-diabetic obese patients.
Cir Cir
January 2025
Department of General Surgery, Antalya Training and Research Hospital, Antalya, Turkey.
Objective: Dysregulation of lipid metabolism can be one of the pathophysiological mechanisms linking high-density lipoprotein cholesterol (HDL-C) dysfunction to obesity. The aim of the study is to show possible changes in lipid metabolism with atherogenic indices in obese patients after sleeve gastrectomy (SG) surgery.
Method: Thirty patients who had SG surgery for obesity were included in the prospective study.
Background: Cardiovascular-kidney-metabolic (CKM) health, a term recently defined by the American Heart Association, encompasses the interplay among metabolic, chronic kidney, and cardiovascular risk factors. We aimed to investigate the predictive significance of CKM disorders with the risk of cognitive decline and Alzheimer's disease (AD) and AD-related dementia (ADRD) mortality in a multiethnic population.
Method: We analyzed a cohort of 6,440 adults aged 45-84 who participated in the Multiethnic Study of Atherosclerosis, with a baseline survey conducted in 2000-2002, and were followed through to December 2015.
Public Health.
Alzheimers Dement
December 2024
Division of Geriatrics, Department of Internal Medicine, University of Sao Paulo Medical School, São Paulo, São Paulo, Brazil.
Background: The association of serum cholesterol with cognitive performance is controversial. Besides, little is known about the association of triglycerides to HDL cholesterol ratio (TG/HDL-c) with cognitive performance. We aimed to verify the association of baseline cholesterol, triglyceride, and TG/HDL-c levels with cognitive decline in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) during eight years of follow-up.
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Alzheimers Dement
December 2024
South Texas Alzheimer's Disease Research Center, Harlingen, TX, USA.
Background: Cognitive impairment is associated with mortality. However, evidence using population-based studies is scarce, is limited to one cognitive assessment, and lacks the inclusion of non-fatal adverse health outcomes. Therefore, we aimed this study to (i) investigate the association of cognitive function with mortality and cardiovascular risk and (ii) determine whether cognitive tests improve the risk-stratification of endpoints beyond conventional risk factors.
View Article and Find Full Text PDFBackground: The prevalence of dementia in populations that are underrepresented in research is projected to increase with population aging. Latino and Black individuals, the largest underrepresented populations in the US, experience a higher dementia burden than non-Hispanic White individuals, which is not explained by ethnoracial biological factors. Disparities in structural and social determinants of health may contribute to the preponderance of medical conditions known to increase dementia risk, including potentially modifiable factors in Latino and Black communities.
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