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Assessment of Negative Symptoms in Schizophrenia: From the Consensus Conference-Derived Scales to Remote Digital Phenotyping.
Brain Sci
January 2025
Department of Mental and Physical Health and Preventive Medicine, School of Medicine, University of Campania Luigi Vanvitelli, Largo Madonna delle Grazie 1, 80135 Naples, Italy.
The assessment of negative symptoms in schizophrenia has advanced since the 2006 NIMH-MATRICS Consensus Statement, leading to the development of second-generation rating scales like the Brief Negative Symptom Scale and the Clinical Assessment Interview for Negative Symptoms. These scales address the limitations of first-generation tools, such as the inclusion of aspects that are not negative symptoms and the lack of assessment of the subject's internal experience. However, psychometric validation of these scales is still in progress, and they are not yet recommended by regulatory agencies, thus limiting their use in clinical trials and settings.
View Article and Find Full Text PDFPsychometric comparison of two short versions of the Perceived Stress Scale (PSS-4) in a representative sample of the German population.
Front Psychol
January 2025
Medical Psychology and Medical Sociology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Perceived stress is a construct of crucial importance to health and well-being, necessitating the provision of economic, psychometrically sound instruments to assess it in routine clinical practice and large-scale survey studies. Two competing short versions of the Perceived Stress Scale (PSS), each consisting of four items, have been proposed. In the present study, we compare the two in a sample representative of the German general population ( = 2,527).
View Article and Find Full Text PDFEfficacy of Modified Electroconvulsive Therapy in Treatment-Resistant Schizophrenia.
Alpha Psychiatry
November 2024
Department of Psychiatry, Wuhan Wudong Hospital, Wuhan, China.
Objective: The aim of the study was to investigate the therapeutic effects of modified electroconvulsive therapy (MECT) in combination with risperidone tablets and psychotherapy in the treatment of patients with treatment-resistant schizophrenia (TRS).
Methods: Patients with TRS admitted to the psychiatric department of our hospital between January 2018 and December 2019 were selected as study participants. They were randomly divided into a control group and a study group, with the control group receiving risperidone tablets and psychotherapy, and the study group undergoing MECT as well as the control group treatment.
Exploring the Potential of Psychedelics in the Treatment of Headache Disorders: Clinical Considerations and Exploratory Insights.
Curr Pain Headache Rep
January 2025
Northwell Health Department of Neurology, New York, NY, USA.
Purpose Of Review: Exploration of the potential of serotonergic psychedelic drugs, such as psilocybin and LSD, as potential treatments for headache disorders. This review addresses the need for well-informed physician guidelines and discusses mechanisms, safety, and efficacy of these treatments. Further research, including the consideration of combination with psychotherapy, is needed.
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