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Coup de Sabre is a subset of localized linear scleroderma disease influenced by autoimmune, vascular, and genetic factors. The disease often follows an active, relapsing, and remitting course causing the development of permanent sequelae, such as tissue atrophy, pigment alterations, and bony deformities. Treatment strategies have ranged from surgical to injectable and medical management approaches with varying success.
View Article and Find Full Text PDFNeuroimaging and Clinical Features of Parry-Romberg Syndrome and Linear Morphea En-coup-de-sabre in a Large Case Series.
Acad Radiol
March 2025
Department of Radiology, University of California San Francisco, San Francisco, CA. Electronic address:
Rationale And Objectives: Parry-Romberg Syndrome (PRS) and linear morphea en-coup-de-sabre (ECDS) are rare neurocutaneous disorders characterized by unilateral progressive hemifacial atrophy and linear scleroderma, respectively. Imaging is important for assessing soft tissue and intracranial involvement, though literature is limited to case reports and series . We aim to describe radiologic and clinical epidemiologic features of PRS and ECDS.
View Article and Find Full Text PDFEfficacy and safety of platelet-rich plasma therapy in systemic sclerosis and localized scleroderma; a systematic review.
Arch Dermatol Res
February 2025
Skin Repair Research Center, Jordan Dermatology and Hair Transplantation Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Systemic sclerosis (SSc) and localized scleroderma (LoSc) are rare connective tissue diseases that are identified by skin thickening and hardening with different mechanisms of action. Although advancements in treatments have been achieved in recent years, these conditions remain a major cause of morbidity and currently lack a definitive cure. We sought to evaluate the efficacy and safety of platelet-rich plasma (PRP) treatment in individuals with LoSc and SSc.
View Article and Find Full Text PDFAdvanced Neuroimaging and Clinical Findings in a Case of Linear Scleroderma En Coup De Sabre Presenting With Seizures.
Cureus
November 2024
Radiology, Grupo CT Scanner, Mexico City, MEX.
Scleroderma is a rare connective tissue disease categorized as systemic or localized. Linear subtype of localized scleroderma usually manifests as a cutaneous linear scar-like lesion most commonly on the scalp. It may present with neurologic, ophthalmologic, and rheumatologic symptoms.
View Article and Find Full Text PDFLinear Scleroderma En Coup de Sabre: A Case Series With Eyelid Involvement and Management.
Ophthalmic Plast Reconstr Surg
December 2024
Linear scleroderma en coup de sabre is a rare subtype of localized scleroderma. It is typically characterized by linear sclerosis and atrophy of the skin and underlying dermis affecting the frontoparietal region above the brow. The linear sclerotic lesions rarely extend into the upper eyelid.
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