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[A retrospective cohort study of the effect of zolendronic acid on mandibular bone optical density in cancer patients].
Stomatologiia (Mosk)
June 2024
South-Ural State Medical University, Chelyabinsk, Russia.
The Aim The Study: To analyze the density of the mandible in cancer patients during treatment with zoledronic acid.
Materials And Methods: A retrospective cohort study included 45 patients with cancer aged 26-81 years (average age 55±12.88 years), of whom 14 patients had bone metastases (=14) and took 4 mg of zolendronic acid once every 28 days.
Targeted Radiation and Immune Therapies-Advances and Opportunities for the Treatment of Prostate Cancer.
Pharmaceutics
January 2023
University of Wisconsin Carbone Cancer Center, 1111 Highland Avenue, Madison, WI 53705, USA.
Prostate cancer is the most diagnosed malignancy in men in the United States and the second leading cause of cancer-related death. For localized disease, radiation therapy is a standard treatment that is often curative. For metastatic disease, radiation therapy has been primarily used for palliation, however, several newer systemic radiation therapies have been demonstrated to significantly improve patient outcomes and improve survival.
View Article and Find Full Text PDFStrontium-89 plus zoledronic acid versus zoledronic acid for patients with painful bone metastatic breast cancer.
J Bone Miner Metab
November 2022
Department of Breast Oncology and Surgery, Tokyo Medical University Hospital, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Introduction: β-ray strontium-89 (Sr-89) intra-irradiation therapy has been approved and clinically used to reduce bone metastasis pain not alleviated by bone-modifying agents, external radiation, and analgesic agents. We examined the efficacy of zoledronic acid (ZOL) and Sr-89 combination therapy compared with ZOL alone in breast cancer patients with bone metastases.
Materials And Methods: A randomized controlled trial was conducted on breast cancer patients with bone metastasis to compare the efficacy between ZOL monotherapy and ZOL plus Sr-89 combination therapy.
A novel approach for rapid Sr determination in seawater samples is developed. For the first time in the radioanalytical application, the features of the synthetic zeolite Z4A and a highly selective material for Sr separation were synergically employed. Seawater composition significantly reduces Sr yield on highly selective solid-phase extraction materials, making the preconcentration step essentially important but laborious and time-consuming.
View Article and Find Full Text PDFANALGESIC EFFECT OF VARIOUS RADIOPHARMACEUTICALS IN THE COMPLEX TREATMENT OF METASTATIC BONE DISEASE.
Probl Radiac Med Radiobiol
December 2021
National Cancer Institute, 22/43 Lomonosova Str., Kyiv, 03022, Ukraine.
Objective: The study objective was to investigate and compare the effectiveness of different radiopharmaceuticalsin the treatment of metastatic bone disease.
Materials And Methods: Cancer patients (n = 150, average age (55 ± 11.6) years, 95 females, 55 males) having gotvarious primary tumors and metastatic bone disease were given medical treatment at the Department of NuclearMedicine of the National Institute of Cancer.
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