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http://dx.doi.org/10.2527/jas1966.2541123xDOI Listing

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Background/objectives: Water-soluble vitamins, comprising the B-complex vitamins and vitamin C, are essential for normal growth, cellular metabolism, and immune function in pediatric populations. Due to limited storage in the body, these vitamins require consistent intake to prevent deficiencies. Pediatric populations, particularly infants and young children, face a heightened risk of both deficiency and, in rare cases, toxicity due to varying dietary intake and increased developmental needs.

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A previously healthy female infant was brought to the paediatrics outpatient department by her mother reporting increased irritability and swelling behind her left shoulder, accompanied by restricted movement in her left arm. The irritability had been present for the past 5 months, with swelling also noticed at that time, gradually increasing in size. On examination, a large, firm, immobile mass was detected on the left scapular region.

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Introduction: Recalcirant warts are resistant to conventional therapeutic option with high recurrence rate. In recent year, treatment of warts with different immunotherapeutic agent has shown good results, as it regulate epidermal cell proliferation and are involved in the formation of anti microbial peptides. Hence, this study was undertaken to evaluate the efficacy of immunotherapy with intralesional vitamin D in wart.

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Article Synopsis
  • Excessive vitamin D supplementation can lead to toxicity, which is uncommon but can cause serious symptoms primarily due to high calcium levels in the blood (hypercalcemia).
  • A case study is presented involving a young child who developed posterior reversible encephalopathy syndrome (PRES) alongside complications like high blood pressure, acute kidney failure, and respiratory issues, all linked to vitamin D toxicity.
  • This report aims to educate healthcare providers about the potential severe effects of high vitamin D levels in children and stresses the need for proper safety guidelines for vitamin supplementation among families.
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