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Transperineal 3D fusion imaging-guided targeted microwaves ablation for low to intermediate-risk prostate cancer: results of a phase I-II study.
Minim Invasive Ther Allied Technol
November 2024
Division of Urology, Department of Surgical Sciences, Molinette Hospital, University of Turin, Turin, Italy.
Article Synopsis
- Targeted microwave ablation (TMA) shows promise as a safe and effective treatment for localized prostate cancer, based on a pilot trial involving 11 patients.* -
- No severe complications were reported, and a significant percentage of patients exhibited no cancer in the treated area after follow-up, although new cancer foci were found in some cases.* -
- The study acknowledges limitations such as a small sample size, short follow-up duration, and absence of a comparison group, but supports the potential of TMA combined with fusion imaging for prostate cancer therapy.*
The value of Ga-PSMA PET/CT in the diagnosis of intracapsular prostate cancer with a poor prognosis.
Discov Oncol
July 2024
Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, 68Th Changle Road, Nanjing, 210006, China.
Objective: To evaluate the diagnostic value of Ga-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) for intracapsular prostate cancer with a poor prognosis (PPC) and no extracapsular invasion or distant metastasis.
Methods: The PET/CT images and clinical data of 221 patients were retrospectively analyzed. These patients all had clear pathological results.
Surgical treatment and outcome of sterile prostatic cysts in dogs.
Vet Surg
July 2021
Department of Veterinary Science, University of Turin, Turin, Italy.
Objective: To describe the surgical treatment and outcome of a large cohort of dogs with sterile prostatic cysts (PCs).
Study Design: Retrospective study.
Animals: Forty-four client-owned dogs.
Impact of music on anxiety and pain perception among men undergoing prostate biopsy: Synthesis of qualitative literature.
Complement Ther Clin Pract
May 2021
Division of Urology, University Hospital "Ospedali Riuniti", Department of Clinical, Special and Dental Sciences, Marche Polytechnic University, Ancona, Italy. Electronic address:
Prostate biopsy (PB) is typically well tolerated, with a low risk of major complications. Pain during PB was significantly decreased by the addition of intracapsular lidocaine anesthesia. However, PB is invasive procedure and can be a distressing experience for patients.
View Article and Find Full Text PDFProstate field cancerization and exosomes: Association between CD9, early growth response 1 and fatty acid synthase.
Int J Oncol
April 2020
Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, CA 92618, USA.
Intracapsular and well‑defined adenocarcinomas of the prostate are often surrounded by tissue areas that harbor molecular aberrations, including those of genetic, epigenetic and biochemical nature. This is known as field cancerization, or a field effect and denotes a state of pre‑malignancy. Such alterations in histologically normal tumor‑adjacent prostatic tissues have been recognized as clinically important and are potentially exploitable as biomarkers of disease and/or targets for preventative/therapeutic intervention.
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