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Indomethacin-Induced Gastric Ulcer in Rats: Gastroprotectivity of in Water.
Pharmaceuticals (Basel)
December 2024
Department of Pathology, Faculty of Veterinary Medicine, Ataturk University, Erzurum 25240, Türkiye.
The plant . is employed in both raw and cooked forms for the treatment of gastric diseases, as an expectorant, and for the treatment of warts and the enhancement of urine. A review of the scientific literature revealed no studies investigating the effect of (MN) water extract on gastric diseases.
View Article and Find Full Text PDFCrocin exerts improving effects on indomethacin-induced small intestinal ulcer by antioxidant, anti-inflammatory and anti-apoptotic mechanisms.
Vet Res Forum
December 2019
Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Crocin is a plant-derived carotenoid and bears potent antioxidant property. Ranitidine (a histamine H receptor blocker) is used for peptic ulcer treatment. The present study was planned to investigate the effects of crocin and ranitidine on indomethacin-induced ulcer in small intestine of rats.
View Article and Find Full Text PDFPharmacological interventions for acute pancreatitis.
Cochrane Database Syst Rev
April 2017
Department of Surgery, Royal Free Campus, UCL Medical School, Royal Free Hospital, Pond Street, London, UK, NW3 2QG.
Background: In people with acute pancreatitis, it is unclear what the role should be for medical treatment as an addition to supportive care such as fluid and electrolyte balance and organ support in people with organ failure.
Objectives: To assess the effects of different pharmacological interventions in people with acute pancreatitis.
Search Methods: We searched the Cochrane Central Register of Controlled Trials (CENTRAL, 2016, Issue 9), MEDLINE, Embase, Science Citation Index Expanded, and trial registers to October 2016 to identify randomised controlled trials (RCTs).
Changes in contractile activity of the large intestine in rabbits during the poststress period before and after blockade of muscarinic and nicotinic receptors.
Bull Exp Biol Med
October 2013
Department for Physiology of Visceral Systems, Research Institute of Experimental Medicine, Northwestern Division of the Russian Academy of Medical Sciences, Saint Petersburg, Russia.
The rabbits were exposed twice to stress, fixation to a frame in the supine position, for 60 min. Contractile activity of all portions of the large intestine was shown to increase significantly during the poststress period. These changes were not observed under conditions of blockade of muscarinic and nicotinic receptors.
View Article and Find Full Text PDFEffects of muscarinic agents on chick choroids in intact eyes and eyecups: evidence for a muscarinic mechanism in choroidal thinning.
Ophthalmic Physiol Opt
May 2013
Department of Biomedical Sciences and Disease, The New England College of Optometry, Boston, MA, USA.
Purpose: In chicks, ocular growth inhibition is associated with choroidal thickening and growth stimulation with choroidal thinning, suggesting a mechanistic link between the two responses. Because muscarinic antagonists inhibit the development of myopia in animal models by a non-accommodative mechanism, we tested the hypothesis that agonists would stimulate eye growth and thin the choroid. We also hypothesized that the effective growth-inhibiting antagonists would thicken the choroid.
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