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Effect of the post-reserpine adrenergic block on thrombocytopoiesis and thrombocyte aggregation in rats.
Acta Physiol Pharmacol Bulg
February 1990
Department of Physiology, Higher Medical Institute, Varna.
The effect of the post-reserpine adrenergic block (2 mg/kg for 3 and 6 days) on thrombocytopoiesis, bone marrow megakaryocytes (MKC) and thrombocyte aggregation was studied. A slight decrease in thrombocytes and a significant inhibition of 75selenomethionine incorporation in the newly-formed thrombocyte, more pronounced after 6-day reserpine treatment, was observed. The megakaryocytogram of the rats treated with reserpine for 3 and for 6 days manifested a similar significant decrease in MKC--as a total number and their separate stages.
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