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Chem Biodivers
January 2025
BRiCM: Bangladesh Reference Institute for Chemical Measurements, Natural Product Chemistry, Dhaka, 1205, Dhaka, BANGLADESH.
Introduction: Ethnomedicinal plants in Asia offer a promising, low-side-effect alternative to synthetic drugs for treating fungal infections, one of the most widespread communicable diseases caused by pathogenic fungi. Despite being underexplored, the region's rich plant diversity holds the potential for developing effective antifungal drugs. Research is increasingly focused on bioactive compounds from these plants, which show strong antifungal properties and may serve as leads for new drug development.
View Article and Find Full Text PDFInt J Food Microbiol
December 2024
Department of Food Engineering and Technology, School of Food Engineering, Universidade Estadual de Campinas, São Paulo, Brazil. Electronic address:
Bread is a greatly consumed bakery product worldwide. Unfortunately, it is an optimal substrate for fungal contamination and deterioration (aw > 0.95), commonly caused by the genera Penicillium, Paecilomyces, and Aspergillus, resulting in significant economic losses.
View Article and Find Full Text PDFMicrob Pathog
February 2025
Universidade Regional Do Cariri - URCA, Rua Cel. Antônio Luiz, 1161 - Pimenta, Crato, CE, Brazil.
Candidiasis is an infectious disease caused by some fungi of the genus Candida. In Brazil, the incidence rate is higher than in European countries and the United States, and health problems occur mainly due to the virulence factors of the fungi, which have made treatment with commercial drugs difficult. Considering the context, plants rich in phenolic compounds, such as those of the genus Piper, have been studied due to their antimicrobial properties.
View Article and Find Full Text PDFFuture Microbiol
November 2024
Department of Clinical Analysis & Biomedicine, State University of Maringá, Paraná, Brazil.
Peptides
December 2024
Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México (ICF-UNAM), Av. Universidad S/N, Chamilpa, Cuernavaca, Morelos 62210, México. Electronic address:
Amidst the health crisis caused by the rise of multi-resistant pathogenic microorganisms, Antimicrobial Peptides (AMPs) have emerged as a potential alternative to traditional antibiotics. In this sense, Cm-p5 is an AMP with fungistatic activity against the yeast Candida albicans. Its antimicrobial activity and selectivity have been well characterized; however, the mechanism of action is still unknown.
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