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Article Synopsis
  • A 23-year-old South Asian man developed a darkly pigmented papule on his scalp, which grew within a pre-existing warty plaque present since birth.
  • The papule showed characteristics indicative of basal cell carcinoma (BCC) when examined and biopsied, confirming it developed from a sebaceous naevus.
  • Sebaceous naevi are benign skin lesions that can develop into malignancies like BCC in a small percentage of cases, especially in adults.
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Article Synopsis
  • The case study discusses an 89-year-old woman's rare skin condition involving clonal seborrheic keratosis (SK) accompanied by Bowen disease (BD), which is a form of squamous cell carcinoma in situ.
  • Histopathological analysis showed characteristics of both conditions, including abnormal cell growth and changes in cell structure, indicating a transformation from SK to BD.
  • The findings suggest that the lesions are interconnected rather than independent, highlighting a complex interaction where neoplastic cells in SK evolved into BD with sebaceous differentiation.
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Atypical Nevus Sebaceus at an Unusual Location Treated with Carbon Dioxide Laser: A Case Report.

Clin Cosmet Investig Dermatol

December 2022

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, Indonesia.

Article Synopsis
  • * During puberty, NS lesions can evolve into verrucous plaques due to androgen influence and have the potential to develop into secondary tumors, with a small percentage being malignant.
  • * A case study highlighted an 18-year-old male with atypical NS on his chest, diagnosed through histopathology, and successfully treated with CO laser, indicating the importance of further examination for unusual lesions.
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Background/aim: Sebaceous gland ectopia (SGE) defines the presence of normal sebaceous tissue in an unusual location. This condition is rare and was first described in ectodermal-derived organs, such as the oral cavities and palms, and later in endodermal-derived tissues including the esophagus. SGE of the esophagus is believed to represent a form of acquired metaplasia.

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