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Objective: Periorbital necrotizing soft tissue infection (NSTI) is a rare entity caused either by polymicrobial infection (type 1) or Streptococcus pyogenes and/or Staphylococcus species (type 2). A high level of clinical suspicion is necessary to make the diagnosis. We present 3 cases of NSTI illustrating our diagnostic and therapeutic approach.
View Article and Find Full Text PDFInfected pseudoaneurysm caused by suture-mediated vascular closure after ablation of atrial fibrillation: A case report.
Int J Surg Case Rep
January 2025
Department of Cardiology, Tosei General Hospital, Seto, Aichi, Japan.
Introduction: Suture-mediated vascular closure devices have been widely used in catheter ablation, with 0.14-0.3 % incidence of pseudoaneurysm complications.
View Article and Find Full Text PDFAcylase-Based Coatings on Sandblasted Polydimethylsiloxane-Based Materials for Antimicrobial Applications.
Polymers (Basel)
January 2025
Center for Micro-Electro Mechanical Systems (CMEMS), Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.
Indwelling medical devices, such as urinary catheters, often experience bacterial colonization, forming biofilms that resist antibiotics and the host's immune defenses through quorum sensing (QS), a chemical communication system. This study explores the development of antimicrobial coatings by immobilizing acylase, a quorum-quenching enzyme, on sandblasted polydimethylsiloxane (PDMS) surfaces. PDMS, commonly used in medical devices, was sandblasted to increase its surface roughness, enhancing acylase attachment.
View Article and Find Full Text PDFEicosapentaenoic Acid and Docosahexaenoic Acid as an Antimicrobial Agent in Orthopedics-An In Vitro Study About the Race for Surface.
Pathogens
January 2025
Research Laboratory for Biofilms and Implant Associated Infections (BIOFILM LAB), University Hospital for Orthopaedics and Traumatology, Medical University of Innsbruck, Müllerstraße 44, 6020 Innsbruck, Austria.
Background: The burden of prosthetic joint infection in combination with antibiotic-resistant bacterial strains is a rising dilemma for patients experiencing total joint replacements. Around 0.8-2% of patients experience prosthetic joint infections, while up to 21% of patients are considered fatal cases after 5 years.
View Article and Find Full Text PDFCeftobiprole: A therapeutic update.
Am J Health Syst Pharm
January 2025
Pharmacotherapy Department, Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, WA, USA.
Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.
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