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Sphaeropsidin A Loaded in Liposomes to Reduce Its Cytotoxicity and Preserve Antifungal Activity Against .
Molecules
December 2024
Department of Biology, University of Naples Federico II, Via Cinthia, 80126 Naples, Italy.
species constitute the most common cause of fungal infections in humans; the emergence of resistance and biofilm formation by species further threaten the limited availability of antifungal agents. Over the past decade, . has caused significant outbreaks worldwide and has emerged as a human pathogenic fungus that causes diseases ranging from superficial to life-threatening disseminated infections.
View Article and Find Full Text PDFA New Bis-Urea Based Cage Receptor for Anions: Synthesis, Solid State Structures and Binding Studies.
Chem Asian J
January 2025
Department of Pure and Applied Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.
The synthesis and characterization of a novel bis-urea-based cage receptor for anions (3S,15S)-3,15,20,25-tetramethyl-1,4,6,12,14,17,20,25-octaazatricyclo[15.5.5.
View Article and Find Full Text PDF21-Hydroxylase Deficiency Detected in Neonatal Screening: High Probability of False Negativity in Late Onset Form.
Exp Clin Endocrinol Diabetes
January 2025
Department of Children and Adolescents, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
Aim: Despite the high sensitivity of neonatal screening in detecting the classical form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, one of the unclear issues is identifying asymptomatic children with late onset forms. The aim of this nationwide study was to analyse the association between genotype and screened level of 17-hydroxyprogesterone in patients with the late onset form of 21-hydroxylase deficiency and to quantify false negativity.
Methods: In the Czech Republic, 1,866,129 neonates were screened (2006-2022).
Synthesis of Novel Cu(II), Co(II), Fe(II), and Ni(II) Hydrazone Metal Complexes as Potent Anticancer Agents: Spectroscopic, DFT, Molecular Docking, and MD Simulation Studies.
ACS Omega
September 2024
Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Suleyman Demirel University, Isparta 32260, Türkiye.
Metal complexes [FeL], [NiL]·HO, [CuL], and [CoL]·HO were formed by the ligand (, 4-fluoro-'-(2-hydroxybenzylidene)benzohydrazide) reacting with Fe(OAc), Ni(OAc)·4HO, Cu(OAc)·HO, and Co(OAc)·4HO. The produced compounds were characterized using a variety of methods, such as NMR, UV-vis, FT-IR, magnetic susceptibility, elemental analysis, and molar conductivity. The spectrum of the data indicates that the geometry of the complex molecular structures is octahedral with six coordination sites.
View Article and Find Full Text PDFPrevalence of oral submucous fibrosis linking with Areca Nut usage among Indians.
Bioinformation
July 2024
Department of Periodontics, Pacific Dental College and Research Center, Udaipur, India.
Article Synopsis
- * Out of the participants, 1645 were identified as arecanut users, and the study found that 46.36% of the population chews arecanut.
- * The prevalence of OSMF was reported to be 12.9%, with ongoing research needed to fully understand the causes and mechanisms behind this condition.
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