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Non-metastatic Nephrogenic Hepatic Dysfunction (Stauffer Syndrome) and Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in a Patient With Renal Cell Carcinoma Coinciding With Liposarcoma.
Cureus
March 2024
Nephrology, Veterans Affairs Medical Center, Mountain Home, Johnson City, USA.
Article Synopsis
- Stauffer syndrome is a health condition that affects the liver and is linked to certain types of tumors, especially those in the kidneys.
- It shows signs like yellow skin (jaundice), high liver enzymes, and sometimes a swollen liver or spleen, but not because of a blockage.
- This syndrome can happen with other cancers too, and in one case, a 76-year-old patient had problems with both their liver and a tumor in their kidneys.
Stauffer Syndrome as the Initial Presentation of Advanced Metastatic Prostate Cancer.
Cureus
April 2023
Pathology, BronxCare Health System, Bronx, USA.
Stauffer's syndrome is a paraneoplastic syndrome that has historically been associated with renal cell carcinoma. It is defined by the anicteric elevation of liver enzymes in the absence of liver metastasis, and the reversibility of clinical and biochemical changes upon treatment of the primary pathology. Here, we discuss the rare presentation of Stauffer's syndrome in a patient with advanced metastatic prostate cancer.
View Article and Find Full Text PDFRenal cell carcinoma presenting as painless jaundice and unintentional weight loss.
Am J Clin Exp Urol
December 2022
Department of Urology, Galway University Hospital Galway, Ireland.
Painless jaundice and unexplained weight loss is an exceedingly rare presentation for renal cell carcinoma (RCC). Such a presentation is more typical of a hepatocellular pathology. Stauffer syndrome is a paraneoplastic syndrome seen in RCC and is characterized by deranged hepatic enzymes and in association with fever, fatigue and weight loss.
View Article and Find Full Text PDFRenal cell carcinoma presented with a rare case of icteric Stauffer syndrome: A case report.
World J Clin Cases
September 2022
Medical University of Sofia, Sofia 1431, Bulgaria.
Background: Paraneoplastic syndromes remain poorly understood and manifest as multifaceted clinical symptoms, making their diagnosis difficult. Cholestasis can be observed in various malignancies. In rare cases, it can be a paraneoplastic manifestation, most often associated with renal cell carcinoma and other urogenital tumors, as well as with bronchial carcinoma.
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