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Membranous nephropathy (MN) is a kidney disease characterized by deposition of immune complexes and complement on the outer aspect of the glomerular capillary wall. It is responsible for a loss of serum proteins in the urine and kidney failure. During the last ten years, considerable progress has occurred in the understanding of the molecular bases of the disease with the description of three distinct mechanisms in humans.
View Article and Find Full Text PDFJ Matern Fetal Neonatal Med
December 2008
Department of Obstetrics and Gynecology, Amphia Hospital Breda, Breda, The Netherlands.
Background: Uterine contractions during labor can be monitored by external tocodynamometry or by the use of an intrauterine pressure catheter (IUPC). Since an IUPC measures the frequency of contractions as well as their strength and duration, it is thought to be more accurate than external tocodynamometry. However, limited evidence on this subject suggests that IUPC may not improve maternal or perinatal outcomes.
View Article and Find Full Text PDFJ Mol Signal
December 2006
Department of Biochemistry & Molecular Biology, Univ, of Texas Medical Branch, Galveston TX 77555-0645, USA.
Background: The effects of estrogens on dopamine (DA) transport may have important implications for the increased incidence of neurological disorders in women during life stages when hormonal fluctuations are prevalent, e.g. during menarche, reproductive cycling, pregnancy, and peri-menopause.
View Article and Find Full Text PDFJ Reprod Med
August 2005
Department of Obstetrics, Christiana Care Health Services, Newark, Delaware, USA.
Objective: To compare the rate of extramembranous placement between 2 types of intrauterine pressure catheter.
Study Design: Women were randomized to a transducer-tipped intrauterine pressure catheter or an air-coupled intrauterine pressure catheter from October 1998 to August 1999. Women were eligible for the study if their attending physicians decided to place an intrauterine pressure catheter.
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