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Identification of the Polymerizing Glycosyltransferase Required for the Addition of d-Glucuronic Acid to the Capsular Polysaccharide of .
Biochemistry
January 2025
Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
is the leading cause of food poisoning in Europe and North America. The exterior surface of this bacterium is encased by a capsular polysaccharide that is attached to a diacyl glycerol phosphate anchor via a poly-Kdo (3-deoxy-d--oct-2-ulosinic acid) linker. In the HS:2 serotype of NCTC 11168, the repeating trisaccharide consists of d-ribose, -acetyl-d-glucosamine, and d-glucuronate.
View Article and Find Full Text PDFKalamari: a representative set of genomes of public health concern.
Microbiol Resour Announc
January 2025
Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Kalamari is a resource that supports genomic epidemiology and pathogen surveillance. It consists of representative genomes and common contaminants. Kalamari also contains a custom taxonomy and software for downloading and formatting the data.
View Article and Find Full Text PDFFoodborne Infections and : Current Primary Prevention Tools and Future Perspectives.
Vaccines (Basel)
December 2024
Food Hygiene and Nutrition Service, Local Health Unit 3, Department of Prevention, 16142 Genoa, Italy.
is considered the major zoonotic and foodborne pathogen responsible for human infections. It includes the serovars causing typhoid fever ( and ) and the non-typhoidal salmonella (NTS) serovars ( and ), causing enteric infections known as "Salmonellosis". NTS represents a major public health burden worldwide.
View Article and Find Full Text PDFOptimization of the Extraction Protocol for Pacific Ciguatoxins from Marine Products Prior to Analysis Using the Neuroblastoma Cell-Based Assay.
Mar Drugs
January 2025
Institut de Recherche pour le Développement (IRD), UMR 241-SECOPOL (IFREMER, ILM, IRD, UPF), P.O. Box 6570, 98702 Faa'a, Tahiti, French Polynesia.
Ciguatera poisoning (CP) is caused by the consumption of marine products contaminated with ciguatoxins (CTXs) produced by dinoflagellates of the genus . Analytical methods for CTXs, involving the extraction/purification of trace quantities of CTXs from complex matrices, are numerous in the literature. However, little information on their effectiveness for nonpolar CTXs is available, yet these congeners, contributing to the risk of CP, are required for the establishment of effective food safety monitoring programs.
View Article and Find Full Text PDFA Comparative Study of the In Vitro Intestinal Permeability of Pinnatoxins and Portimine.
Mar Drugs
January 2025
Toxicology of Contaminants Unit, Fougères Laboratory, ANSES (French Agency for Food, Environmental and Occupational Health & Safety), 35306 Fougères, France.
The pinnatoxins (PnTXs) and portimines, produced by , have been detected in several countries, raising concerns for human health. Although no human poisoning from these toxins has been reported so far, they have been shown to distribute throughout the rodent body after oral administration. Therefore, we investigated the impact of PnTX analogs (PnTX-A, -E, -F, -G, and -H) and portimine (8, 16, and 32 ng/mL) on intestinal barrier integrity and their oral bioavailability using human Caco-2 cell monolayers treated for 2, 6, and 24 h.
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