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Circadian rhythm and lithium response in bipolar disorder: Insights from actigraphy and NR1D1 polymorphism.
Chronobiol Int
January 2025
Department of Child and Adolescent Psychiatry, Balıkesir Atatürk City Hospital, Balıkesir, Turkey.
Lithium has long been used as a cornerstone mood stabilizer in the treatment of bipolar disorder (BD). However, reliable biomarkers that can predict which patients will respond better to lithium are still lacking. This study aims to evaluate the potential of NR1D1 gene SNP; rs2071427 and actigraphic measurements in predicting lithium response.
View Article and Find Full Text PDFCircadian Modulation of Behavioral Stress Responses in Zebrafish Is Age-Dependent.
J Exp Zool A Ecol Integr Physiol
January 2025
Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Emilia-Romagna, Italy.
In the wild, stressors occur with varying likelihood throughout the day, leading animals to evolve plastic stress responses that exhibit circadian rhythmicity. In mammals, studies have revealed that the circadian plasticity of stress response may differ with age. However, such developmental effects have been largely overlooked in other vertebrate groups.
View Article and Find Full Text PDFLiving in Biological Darkness II: Impact of Winter Habitual Daytime Light on Night-Time Sleep.
Eur J Neurosci
January 2025
Institute of Physiology, Sleep Research & Clinical Chronobiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Timing and architecture of sleep are co-driven by circadian rhythms modulated by their major Zeitgeber light and darkness. In a natural environment, one is exposed to 3.000 lx (cloudy winter sky) to 100.
View Article and Find Full Text PDFSleep-wake patterns of fencing athletes: a long-term wearable device study.
PeerJ
January 2025
Department of Graduate, Nanjing Sport Institute, Nanjing, Jiangsu, China.
Objective: Sleep is the most efficient means of recovery for athletes, guaranteeing optimal athletic performance. However, many athletes frequently experience sleep problems. Our study aims to describe the sleep-wake patterns of fencing athletes and determine whether factors, such as sex, competitive level and training schedules, could affect the sleep-wake rhythm.
View Article and Find Full Text PDFProlonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors.
J Clin Transl Sci
December 2024
College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Introduction: Older age significantly increases risk for cognitive decline. A growing number of older adults (≥ 65 years) experience cognitive decline that compromises immediate and/or long-term health. Interventions to mitigate cognitive decline are greatly needed.
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