The action of haem, haemoglobin and other haemoproteins on crude and purified delta-aminolaevulate dehydratase of human erythrocyte is described. The results show a feedback inhibition by haem of porphyrin synthesis at the level of erythrocyte delta-aminolaevulate dehydratase. Some kinetic characteristics of this inhibition are described.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270139PMC
http://dx.doi.org/10.1042/bj1010550DOI Listing

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