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A review on the screening methods for the discovery of natural antimicrobial peptides.
J Pharm Anal
January 2025
School of Medicine, Foshan University, Foshan, Guangdong, 528000, China.
Natural antimicrobial peptides (AMPs) are promising candidates for the development of a new generation of antimicrobials to combat antibiotic-resistant pathogens. They have found extensive applications in the fields of medicine, food, and agriculture. However, efficiently screening AMPs from natural sources poses several challenges, including low efficiency and high antibiotic resistance.
View Article and Find Full Text PDFProteomic and peptidomic profiling of spirulina-fortified probiotic powder formulations during in vitro digestion.
Int J Biol Macromol
January 2025
Environmenal Research and Innovation (ERIN) department, Luxembourg Institute of Science and Technology (LIST), 5 avenue des Hauts Fourneaux, L4362 Esch-sur-Alzette, Luxembourg. Electronic address:
This study reports on the influence of lactic acid fermentation on the proteomic and peptidomic profiles of spirulina protein isolate (SPI)-fortified, freeze-dried powders containing living Lacticaseibacillus rhamnosus GG (LGG) cells during in vitro digestion. For comparison, powders fortified with whey protein isolate (WPI) and pea protein isolate (PPI) were also evaluated. Prior to freeze-drying, the powder precursors were either non-treated or fermented.
View Article and Find Full Text PDFCombining Hyperpolarized Xe MR Imaging and Spectroscopy to Non-Invasively Estimate Pulmonary Vascular Resistance.
J Appl Physiol (1985)
January 2025
Medical Physics Graduate Program, Duke University, Durham, North Carolina, United States.
Hyperpolarized Xe MRI/MRS enables quantitative mapping of function in lung airspaces, membrane tissue, and red blood cells (RBCs) within the pulmonary capillaries. The RBC signal also exhibits cardiogenic oscillations that are reduced in pre-capillary pulmonary hypertension (PH). This effect is obscured in patients with concomitant defects in transfer from airspaces to RBCs, which increase RBC oscillation amplitudes.
View Article and Find Full Text PDFSolidified lake sediment with industrial waste and construction waste used as barrier cover material: mechanical strength, water resistance performance, and microscopic analysis.
Environ Technol
January 2025
School of Civil Engineering and Architecture, Wuhan Polytechnic University, Wuhan, People's Republic of China.
This study introduces a novel landfill cover material, employing lake sediment as a substrate, stabilised with fly ash, slag, desulfurisation gypsum and construction waste. The mechanical properties, including shear strength parameters, unconfined compressive strength, hydraulic conductivity, volumetric shrinkage, and water content, of the solidified sludge were evaluated. The microscopic mechanism of the solidified sludge were investigated through XRD, FTIR, and SEM-EDS techniques.
View Article and Find Full Text PDFBioinspired Superwettability Surface Strategies for Condensation Heat Transfer.
ACS Nano
January 2025
Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, P. R. China.
Along with the development of miniaturization, integration, and high power of electronic chips in the 5G and artificial intelligence era and their urgent need for technologies enabled to solve high heat flux dissipation in limited space, investigating bioinspired extreme superwettability surfaces with high-efficiency condensation heat transfer (CHT) performance has attracted great interest in academic and industrial communities. Compared with filmwise condensation of flat hydrophilic surfaces featured with continuous liquid films, dropwise condensation of flat hydrophobic surfaces is a more efficient type of energy transport way. However, discrete condensate drops can only shed off the hydrophobic flat surfaces under gravity until their sizes reach the capillary length of liquid, e.
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