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Characterization of the GH72 family of Laminarin/Lichenin transferases and their roles in cell wall biogenesis.
Cell Surf
June 2025
Department of Biological Sciences, SUNY University at Buffalo, Buffalo, NY 14260, United States.
In vegetative hyphae, chitin, β-1,3-glucan (laminarin), and a mixed β-1,3-/β-1,4-glucan (lichenin) are the major cell wall polysaccharides. GH72 enzymes have been shown to function as β-1,3-glucanases and glucanosyltransferases and can function in crosslinking β-1,3-glucans together. To characterize the enzymatic activities of the enzymes, we expressed GEL-1 with a HIS6 tag in A chimeric maltose binding protein:GEL-2 was produced in .
View Article and Find Full Text PDFInhibition of Aβ Aggregation by Cholesterol-End-Modified PEG Vesicles and Micelles.
Pharmaceutics
December 2024
Department of Applied Chemistry, Tokyo Metropolitan University, Tokyo 192-0397, Japan.
: This study aimed to design and evaluate Chol-PEG micelles and Chol-PEG vesicles as drug delivery system (DDS) carriers and inhibitors of amyloid-β (Aβ) aggregation, a key factor in Alzheimer's disease (AD). : The physical properties of Chol-PEG assemblies were characterized using dynamic light scattering (DLS), electrophoretic light scattering (ELS), and transmission electron microscopy (TEM). Inhibitory effects on Aβ aggregation were assessed via thioflavin T (ThT) assay, circular dichroism (CD) spectroscopy, and native polyacrylamide gel electrophoresis (native-PAGE).
View Article and Find Full Text PDFNanocellulose-toughened super-stretchable ionic conductive gel fibers for wearable strain sensors.
Int J Biol Macromol
January 2025
College of Textiles, Donghua University, Shanghai 201620, China; Key Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China. Electronic address:
In recent years, conductive gel materials have attracted extensive attention in the field of flexible electronics because of their excellent elasticity. When constructed as gel fibers, they can adapt to greater deformation, be woven, and be assembled with fabrics to make wearable smart devices without compromising comfort. However, gel fibers reported often exhibit insufficient mechanical properties and poor adaptability to different environment.
View Article and Find Full Text PDFBlastocystis ST1: Protein Profile and Specific Serum Immunoglobulin in Irritable Bowel Syndrome (IBS) Patients.
Acta Parasitol
January 2025
Department of Animal Biology, Faculty of Science, Damascus University, Damascus, Syria.
Purpose: Blastocystis sp. is a common enteric human parasite, which recently has been linked to gastrointestinal disorders i.e.
View Article and Find Full Text PDFOxidative and nitrative DNA damage induced by industrial chemicals in relation to carcinogenesis.
J Occup Health
January 2025
Department of Environmental Health, University of Fukui School of Medical Science, Eiheiji, Fukui, Japan.
Objectives: Many chemicals have been used for industrial purposes, and some of them are carcinogenic to humans. However, their molecular mechanisms have not been well understood. Reactive oxygen species are generated from industrial chemicals and contribute to carcinogenesis.
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