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Teratological, neurochemical and histomorphic changes in the limbic areas of F1 mice progeny due to co-parental polystyrene nanoplastic exposure.
Toxicology
December 2024
Department of Zoology, IIS (Deemed to be University), Jaipur, Rajasthan, India.
In the present study, co-parental exposure to polystyrene nanoplastics (PS-NPs) elicits profound teratological impacts, including skeletal and visceral malformations, post-natal effects on neonatal growth and neurobehavioral development in F1 progeny. A comprehensive investigation was conducted on Swiss albino mice fetuses, neonates (PND 1-21) and adult mice offsprings (PND 60) following parental exposure during spermatogenesis and oogenesis period, as well as continued maternal exposure during gestation and weaning. The parental mice were administered PS-NPs via oral gavage at low dose (0.
View Article and Find Full Text PDFTeratological abnormalities in hard ticks (Acari: Ixodidae) from Pakistan.
Exp Appl Acarol
December 2024
Department of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Studying teratological abnormalities in ticks are taxonomically important because this poorly understood biological phenomenon causes difficulties in tick's identification. Globally, reports regarding these abnormalities in ticks, reasons of their causes and their impacts are scarce. According to the available published data, there are no studies regarding teratological abnormalities in ticks from Pakistan.
View Article and Find Full Text PDFDevelopmental exposure of antibiotics shortens life span and induces teratogenicity in .
Toxicol Rep
December 2024
Bioinformatics and Molecular Medicine Research Group, Dow Fly Research Lab and Stock Centre, Dow College of Biotechnology, Dow University of Health Sciences, Karachi 75280, Pakistan.
Antibiotics are the major therapeutic arsenal against bacterial infections. Yet, beneath this medical triumph lies an under investigated challenge of the potential teratological and toxicological impacts associated with the use of antibiotics. In the present study, we have explored the teratogenic potential of five commonly used antibiotics (streptomycin, metronidazole, tigecycline, doxycycline and norfloxacin) on Oregon-R strain.
View Article and Find Full Text PDFMOLECULAR AND NEW MORPHOLOGICAL DATA ON NEMATODE HEDRURIS DRATINI FOUND PARASITIZING PSEUDIS MINUTA (ANURA: HYLIDAE).
J Parasitol
December 2024
Centro de Estudios Parasitológicos y Vectores (CEPAVE), Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de La Plata (CCT, CONICET-UNLP), La Plata (1900), Buenos Aires, Argentina.
Hedruris has a worldwide distribution, parasitizing lampreys, fishes, frogs, and lizards. In South America, 4 species have been reported on frogs (Hedruris heyeri, Hedruris juninensis, Hedruris moniezi, and Hedruris mucronifer), 3 on fishes (Hedruris basilichtensis, Hedruris orestiae, and Hedruris suttonae), and 1 on turtles (Hedruris dratini). We examined a frog (Pseudis minuta) found dead in the Pescado stream, Argentina, searching for parasites.
View Article and Find Full Text PDFExposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment.
Int J Toxicol
December 2024
Department of Zoology, Bangalore University, Bangalore, India.
Neuroendocrine regulation is disrupted by di-n-butyl phthalate (DBP) when exposure occurs during the critical periods of fetal development, which can lead to neurological disorders. To evaluate the toxic potential of DBP, it is necessary to conduct teratological studies, which could determine impacts on the development of the fetus. The present study was designed to understand the sequelae of neuroendocrine regulation in one-month-old pups when rats were exposed to DBP (F-F) and during lactation.
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