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Lewy body diseases and the gut.
Mol Neurodegener
January 2025
Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.
Gastrointestinal (GI) involvement in Lewy body diseases (LBDs) has been observed since the initial descriptions of patients by James Parkinson. Recent experimental and human observational studies raise the possibility that pathogenic alpha-synuclein (⍺-syn) might develop in the GI tract and subsequently spread to susceptible brain regions. The cellular and mechanistic origins of ⍺-syn propagation in disease are under intense investigation.
View Article and Find Full Text PDFA community-based father education intervention on breastfeeding practice in Ethiopia: a quasi-experimental study.
BMC Pediatr
January 2025
Department of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Background: Breastfeeding is the cornerstone of a newborn's nutrition, containing crucial nutritional components. While a substantial body of research focuses on mothers, there is limited understanding regarding effective strategies to engage fathers in promoting breastfeeding practices. Therefore, this quasi-experimental study investigated a community-based intervention to improve breastfeeding exclusivity and initiation rates by targeting fathers in breastfeeding education.
View Article and Find Full Text PDFKidney immunology from pathophysiology to clinical translation.
Nat Rev Immunol
January 2025
III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kidney diseases are widespread and represent a considerable medical, social and economic burden. However, there has been marked progress in understanding the immunological aspects of kidney disease. This includes the identification of distinct intrarenal immunological niches and characterization of kidney disease endotypes according to the underlying molecular immunopathology, as well as a better understanding of the pathological roles for T cells, mononuclear phagocytes and B cells and the renal elements they target.
View Article and Find Full Text PDFValorization of nano-scrap carbon iron filings as heterogeneous electro-Fenton catalyst for the removal of anticancer drug: insight into degradation mechanism.
Environ Sci Pollut Res Int
January 2025
Department of Environmental Science and Engineering, Indian Institute of Technology (ISM), Dhanbad, 826004, Jharkhand, India.
This study employs mechanically synthesized nano-scrap carbon iron filings (nSCIF) as a cost-effective and sustainable catalyst in heterogeneous electro-Fenton process. The catalytic behaviour of nSCIF was studied for the oxidation of cytarabine (CBN) under the influence of various experimental parameters such as pH, catalyst dose and applied current density. The highest removal efficiency (~ 99%) was achieved in 90 min of reaction at pH 3, 0.
View Article and Find Full Text PDFEnhanced capacity in cellulose aerogel for carbon dioxide capture through modified by metal-organic framework.
Int J Biol Macromol
January 2025
College of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, PR China. Electronic address:
Microporous metal-organic frameworks (MOF) exhibit excellent carbon dioxide (CO) adsorption performance and selectivity for CO/N separation. However, the challenges associate with the recycling and reuse of MOF powders hinder their practical applications. To address these limitations, a flexible and stable MOF-based composite material was designed by immobilizing UiO-66(Zr)-(OH) onto cellulose nanofibers (CNFs) aerogels (MOF-CNFs), which featured high porosity.
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