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Targeting senescence and GATA4 in age-related cardiovascular disease: a comprehensive approach.
Biogerontology
January 2025
Center for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
The growing prevalence of age-related cardiovascular diseases (CVDs) poses significant health challenges, necessitating the formulation of novel treatment approaches. GATA4, a vital transcription factor identified for modulating cardiovascular biology and cellular senescence, is recognized for its critical involvement in CVD pathogenesis. This review collected relevant studies from PubMed, Google Scholar, and Science Direct using search terms like 'GATA4,' 'cellular senescence,' 'coronary artery diseases,' 'hypertension,' 'heart failure,' 'arrhythmias,' 'congenital heart diseases,' 'cardiomyopathy,' and 'cardiovascular disease.
View Article and Find Full Text PDFReply to: comment on "Early cancer detection by serum biomolecular fingerprinting spectroscopy with machine learning".
Light Sci Appl
January 2025
School of Physics and Technology, National Demonstration Center for Experimental Physics Education, Wuhan University, Wuhan, 430072, China.
Advanced microgrid optimization using price-elastic demand response and greedy rat swarm optimization for economic and environmental efficiency.
Sci Rep
January 2025
Department of Theoretical Electrical Engineering and Diagnostics of Electrical Equipment, Institute of Electrodynamics, National Academy of Sciences of Ukraine, Beresteyskiy, 56, Kyiv-57, Kyiv, 03680, Ukraine.
In this paper, a comprehensive energy management framework for microgrids that incorporates price-based demand response programs (DRPs) and leverages an advanced optimization method-Greedy Rat Swarm Optimizer (GRSO) is proposed. The primary objective is to minimize the generation cost and environmental impact of microgrid systems by effectively scheduling distributed energy resources (DERs), including renewable energy sources (RES) such as solar and wind, alongside fossil-fuel-based generators. Four distinct demand response models-exponential, hyperbolic, logarithmic, and critical peak pricing (CPP)-are developed, each reflecting a different price elasticity of demand.
View Article and Find Full Text PDFEnergy feature extraction and visualization of voltage sags using wavelet packet analysis for enhanced power quality monitoring.
Sci Rep
January 2025
Department of Theoretical Electrical Engineering and Diagnostics of Electrical Equipment, Institute of Electrodynamics, National Academy of Sciences of Ukraine, Beresteyskiy, 56, Kyiv-57, Kyiv, 03680, Ukraine.
Power quality (PQ) disturbances, such as voltage sags, are significant issues that can lead to damage in electrical equipment and system downtime. Detecting and classifying these disturbances accurately is essential for maintaining reliable power systems. This paper introduces a novel approach to voltage sag analysis by employing wavelet packet analysis combined with energy-based feature extraction to enhance PQ monitoring.
View Article and Find Full Text PDFPytaxon: A Python software for resolving and correcting taxonomic names in biodiversity data.
Biodivers Data J
January 2025
Laboratório de Computação Avançada para Biodiversidade (COMBIO). Museu Paraense Emílio Goeldi, Belém, Brazil Laboratório de Computação Avançada para Biodiversidade (COMBIO). Museu Paraense Emílio Goeldi Belém Brazil.
Background: The standardisation and correction of taxonomic names in large biodiversity databases remain persistent challenges for researchers, as errors in species names can compromise ecological analyses, land-use planning and conservation efforts, particularly when inaccurate data are shared on global biodiversity portals.
New Information: We present pytaxon, a Python software designed to resolve and correct taxonomic names in biodiversity data by leveraging the Global Names Verifier (GNV) API and employing fuzzy matching techniques to suggest corrections for discrepancies and nomenclatural inconsistencies. The pytaxon offers both a Command Line Interface (CLI) and a Graphical User Interface (GUI), ensuring accessibility to users with different levels of computing expertise.
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