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Effect of intraoperative noise isolation on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: protocol for a randomized controlled trial.
BMC Anesthesiol
January 2025
Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: Postoperative nausea and vomiting (PONV) are common complications following general anesthesia, particularly in gynecological laparoscopic surgeries. This study aims to evaluate the effect of intraoperative noise isolation on PONV incidence.
Method: This single-center, prospective, randomized controlled trial will enroll 192 adult patients undergoing laparoscopic gynecological surgery.
Error-driven upregulation of memory representations.
Commun Psychol
January 2025
Institute of Psychology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Learning an association does not always succeed on the first attempt. Previous studies associated increased error signals in posterior medial frontal cortex with improved memory formation. However, the neurophysiological mechanisms that facilitate post-error learning remain poorly understood.
View Article and Find Full Text PDFAnalysis of the cardiotoxic and myorelaxant effects of camphor on fish of the Nile tilapia species (Oreochromis niloticus) (Linnaeus 1758).
Sci Rep
January 2025
Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Pará (UFPA), UFPA Campus Belém, Rua Augusto Corrêa No 01 Guamá, Belém, PA, CEP: 66075 - 110, Brazil.
The present study aimed to characterize the behavior and evaluate the electromyographic (EMG), electrocardiographic (ECG), and respiratory responses of Nile tilapia (Oreochromis niloticus) when exposed to different concentrations of Camphor (CPR) as a potential anaesthetic in immersion and recovery baths. The goal was to determine the impact of CPR on muscle, cardiac, and respiratory functions, and assess its suitability as an anesthetic for tilapia. Therefore, juvenile fish (38.
View Article and Find Full Text PDFThe pulsatile brain, pulse pressure, cognition, and antihypertensive treatments in older adults: a functional NIRS study.
J Hum Hypertens
January 2025
Research Centre, Montreal Heart Institute, Montreal, QC, Canada.
Age-related arterial stiffness increases pulsatility that reaches the cerebral microcirculation, compromises cerebrovascular health and lead to cognitive decline. The presence of cardiovascular risk factors (CVRFs) such as high blood pressure can exacerbate this effect. Despite extensive research on the impact of antihypertensive treatments on reducing arterial stiffness, little is known about the impact of antihypertensive treatments on pulsatility in cerebral microcirculation.
View Article and Find Full Text PDFMuscarinic acetylcholine receptor 3 localized to primary endothelial cilia regulates blood pressure and cognition.
Sci Rep
January 2025
Department of Pharmacology and Experimental Therapeutics; MS 1015, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Health Education Building; Room 282E, 3000 Arlington Ave, Toledo, OH, 43614, USA.
We previously demonstrated that the inability of primary endothelial cilia to sense fluid shear stress can lead to nitric oxide (NO) deficiency and cause hypertension (HTN). Decreased biosynthesis of NO contributes to cerebral amyloid angiopathy in Alzheimer's disease (AD) patients through increased deposition of amyloid beta (Aβ). However, the molecular mechanisms underlying the pathogenesis of HTN and AD are incompletely understood.
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