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A Comparative Review of Alternative Fucoidan Extraction Techniques from Seaweed.
Mar Drugs
January 2025
Institute for Bioengineering, The School of Engineering, The University of Edinburgh, Edinburgh EH9 3DW, UK.
Fucoidan is a sulfated polysaccharide found in brown seaweed. Due to its reported biological activities, including antiviral, antibacterial and anti-inflammatory activities, it has garnered significant attention for potential biomedical applications. However, the direct relationship between fucoidan extracts' chemical structures and bioactivities is unclear, making it extremely challenging to predict whether an extract will possess a given bioactivity.
View Article and Find Full Text PDFA Serum D-Fucose Binding Lectin With B Cell Mitogenic Activity From the Grub of the Darkling Beetle Zophobas morio.
J Mol Recognit
January 2025
Unit of Molecular Entomology, Department of Zoology, University of Madras, Chennai, India.
Lectins that can recognize and bind to carbohydrates and glycoconjugates are at the epicentre of research owing to their prospective applications. In the present study, a D-fucose binding lectin from the serum of darkling beetle, Zophobas morio was purified and their mitogenic potential over human B-cells was evaluated. Biochemical assays on the preliminary characterization revealed the occurrence of single D-fucose binding lectin.
View Article and Find Full Text PDFGenomic analysis of Isoptericola halotolerans SM2308 reveals its potential involved in fucoidan degradation.
Mar Genomics
March 2025
State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China. Electronic address:
Marine bacteria play important roles in the degradation and recycling of algal polysaccharides. However, the marine bacteria involved in fucoidan degradation and their degradation pathways remain poorly understood. Here, we report the complete genome sequence of Isoptericola halotolerans SM2308, isolated from a brown algal sample collected from an intertidal zone of the Yellow Sea in China.
View Article and Find Full Text PDFStructure and function of a β-1,2-galactosidase from Bacteroides xylanisolvens, an intestinal bacterium.
Commun Biol
January 2025
Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan.
Galactosides are major carbohydrates that are found in plant cell walls and various prebiotic oligosaccharides. Studying the detailed biochemical functions of β-galactosidases in degrading these carbohydrates is important. In particular, identifying β-galactosidases with new substrate specificities could help in the production of potentially beneficial oligosaccharides.
View Article and Find Full Text PDFOsteoporosis (OP) is a prevalent metabolic bone disease globally. Currently, the development of Traditional Chinese Medicine (TCM) resources to unblock joints, strengthen bones, and enhance muscle function to regulate anti-osteogenic and anabolic metabolism and thus reshape intraosseous homeostasis was an effective way to alleviate OP. The F-E-D formula, comprising Fructus Psoraleae, Eucommia, and Drynariae Rhizoma, has shown efficacy in treating OP.
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