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A case of disseminated blastomycosis in New England.

IDCases

December 2024

University of Vermont, Department of Biomedical and Health Sciences, Burlington, VT, United States.

infections are classified as dimorphic fungal infections commonly seen geographically throughout the Mississippi and Ohio River Valleys, St. Laurence Seaways, as well as the Canadian providences of Ontario Manitoba, and Saskatchewan. Although primarily endemic in the Midwestern United States, there has been a rise in cases throughout New England.

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[Differential analysis of intestinal flora in patients with hepatic blastomycosis based on second-generation sequencing].

Zhonghua Yu Fang Yi Xue Za Zhi

January 2025

Department of Basic Medicine, College of Medicine, Qinghai University, Xining810016, China.

Exploring the variability of the intestinal flora of patients with hepatic blastocysticercosis and searching for members of the intestinal microflora that may play a role in the disease process by means of macro-genome sequencing technology. A case-control study was used to include fecal samples from patients with hepatic vesicular schistosomiasis admitted to Qinghai Provincial People's Hospital between October 2023 and January 2024 and individuals attending health checkups. The experimental group (AE group) consisted of 10 patients with liver vesicular schistosomiasis and the control group (NC group) consisted of 9 individuals attending health checkups.

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Outcomes Associated With Blastomycosis in Solid Organ and Hematopoietic Cell Transplant Recipients.

Transpl Infect Dis

December 2024

Department of Medicine, Section of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.

Introduction: With reports of expanding epidemiology of blastomycosis across the United States, the purpose of this study was to evaluate the incidence and outcomes associated with blastomycosis in solid organ transplant (SOT) and hematopoietic cell transplant (HCT) recipients.

Methods: We conducted a retrospective case series of adult SOT and HCT recipients at a tertiary care medical center between January 1, 2005 and September 30, 2023. Cases were defined as culture-proven blastomycosis.

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Article Synopsis
  • A 35-year-old male presented with back pain and masses on his arms, having a previous sacral lesion suspected to be a fungal infection that was never fully investigated.
  • CT and MRI showed destructive bone lesions indicating a possible disseminated infection, and biopsies confirmed the presence of Blastomyces dermatitidis.
  • Despite initial concerns about his condition, the patient had no neurological deficits and showed improvement with medical treatment, highlighting the importance of clinical evaluation in making surgical decisions for spinal fungal infections.
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Climate Change and Medical Mycology.

Infect Dis Clin North Am

December 2024

Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, ECMM Excellence Center, Auenbruggerplatz 15, Graz 8036, Austria; Translational Mycology, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria. Electronic address:

This review explores how climate change influences fungal disease dynamics, focusing on emergence of new fungal pathogens, increased antifungal resistance, expanding geographic ranges of fungal pathogens, and heightened host susceptibility. Rising temperatures and altered precipitation patterns enhance fungal growth and resistance mechanisms, complicating treatment efforts. Climate-driven geographic shifts are expanding the range of diseases like Valley fever, histoplasmosis, and blastomycosis.

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