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Atraumatic bilateral femoral neck fractures are rare, especially in younger patients and those without significant comorbidities. However, pregnant individuals appear to be at increased risk due to normal physiological changes in calcium balance, leading to transient osteoporosis of the hip. In these individuals, calcium and bone mineral density are generally decreased, reflecting the calcium demands of the developing fetus.

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Introduction: Primary hyperparathyroidism (PHPT) during pregnancy is rare, with the commonest cause being parathyroid adenoma. Parathyroid cysts represent 0.5% of parathyroid lesions.

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Diagnosing primary hyperparathyroidism in pregnancy is difficult due to pregnancy-related changes in parathyroid hormone (PTH); calcium; 1,25 vitamin D; and renal calcium excretion. Parathyroid hormone-related peptide (PTHrP) produced by the placenta adds additional complexity. Our case is the first to demonstrate an increased rate of PTH degradation within a pregnant individual who returned unexpectedly low PTH levels.

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Primary hyperparathyroidism-induced acute pancreatitis in pregnancy: A systematic review with a diagnostic-treatment algorithm.

World J Gastroenterol

August 2024

Department for Sport and Exercise Medicine, Faculty of Kinesiology, University of Zagreb, Zagreb 10000, Croatia.

Background: Primary hyperparathyroidism (PHPT)-induced acute pancreatitis (AP) during pregnancy has rarely been described. Due to this rarity, there are no diagnostic or treatment algorithms for pregnant patients.

Aim: To determine appropriate diagnostic methods, therapeutic options, and factors related to maternal and fetal outcomes for PHPT-induced AP in pregnancy.

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Article Synopsis
  • Esophageal cancer is very rare in pregnant women, making up only 0.07%-0.1% of malignant tumors during pregnancy, and it progresses quickly, demanding prompt treatment.
  • A case study details a 30-year-old woman diagnosed with squamous cell carcinoma at 32 weeks of pregnancy after experiencing symptoms like hoarseness, dysphagia, and weight loss; the cancer metastasized to her parathyroid region and resulted in significant esophageal dilation.
  • After giving birth, the patient began a chemotherapy treatment plan; her follow-up imaging showed changes in her tumor, highlighting the necessity for vigilance in pregnant patients presenting with symptoms indicative of esophageal cancer.
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