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Single cell derived multicellular meristem: insights into male-to-hermaphrodite conversion and de novo meristem formation in ceratopteris.
Development
January 2025
Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907, USA.
Land plants alternate between asexual sporophytes and sexual gametophytes. Unlike seed plants, ferns develop free-living gametophytes. Gametophytes of the model fern Ceratopteris exhibit two sex types: hermaphrodites with pluripotent meristems and males lacking meristems.
View Article and Find Full Text PDFTarget-agnostic identification of human antibodies to sexual forms reveals cross-stage recognition of glutamate-rich repeats.
Elife
January 2025
Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Circulating sexual stages of ) can be transmitted from humans to mosquitoes, thereby furthering the spread of malaria in the population. It is well established that antibodies can efficiently block parasite transmission. In search for naturally acquired antibodies targets on sexual stages, we established an efficient method for target-agnostic single B cell activation followed by high-throughput selection of human monoclonal antibodies (mAbs) reactive to sexual stages of in the form of gametes and gametocyte extracts.
View Article and Find Full Text PDFImpact of Sports on Female Growth and Pubertal Development: A Cohort Study.
Cureus
December 2024
Department of Sports Medicine, Portuguese Rugby Federation, Lisbon, PRT.
Introduction The participation of women in sports is increasing, and the rising training demands may impact growth and pubertal development. High-intensity sports are often linked to delayed growth and bone maturation due to energy deficits and intense regimens. These factors may increase the risk of injury and musculoskeletal issues.
View Article and Find Full Text PDFKisspeptin and Neurokinin B: roles in reproductive health.
Physiol Rev
January 2025
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.
Kisspeptin and neurokinin B (NKB) play a key role in several physiological processes including in puberty, adult reproductive function including the menstrual cycle, as well as mediating the symptoms of menopause. Infundibular kisspeptin neurons, which co-express NKB, regulate the activity of gonadotropin releasing hormone (GnRH) neurons, and thus the physiological pulsatile secretion of GnRH from the hypothalamus. Outside of their hypothalamic reproductive roles, these peptides are implicated in several physiological functions including sexual behavior and attraction, placental function, and bone health.
View Article and Find Full Text PDFWomen sexual dysfunction in the postpartum period: concept analysis.
Rev Gaucha Enferm
January 2025
Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brasil.
Objective: To analyze the concept of sexual dysfunction in postpartum women and identify their essential attributes, antecedents, and effects.
Method: Concept analysis based on a framework by Walker and Avant, elaborated in eight stages, which were: concept selection; identification of the use of the concept; determination of essential attributes; construction of the model case; additional case; identification of antecedents and effects; and definition of empirical references. Furthermore, an integrative review was carried out simultaneously, with a view to supporting the analysis of the concept.
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