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Effect of lemborexant on sleep architecture in participants with insomnia disorder and mild obstructive sleep apnea.
Sleep Med
December 2024
Eisai Inc., 200 Metro Blvd, Nutley, NJ, 07110, USA.
Objective/background: Comorbid insomnia with obstructive sleep apnea (COMISA) is associated with worse daytime function and more medical/psychiatric comorbidities vs either condition alone. COMISA may negatively impact sleep duration and reduce rapid eye movement (REM) sleep, thereby impairing cognition. These post-hoc analyses evaluated the effect of lemborexant (LEM), a dual-orexin-receptor antagonist approved for adults with insomnia, on sleep architecture in participants with COMISA.
View Article and Find Full Text PDFPoor sleep quality remains a major challenge among tertiary education students in Ghana: A cross-sectional study in a Ghanaian University.
IBRO Neurosci Rep
June 2025
Department of Medical Laboratory Science, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Introduction: Sleep plays a crucial role in health, well-being, and academic performance. Despite the recognized importance of good sleep for students, there is a need for a deeper understanding of the sleep problems faced by university students to inform effective campus support services and interventions. This study aimed to evaluate sleep quality among university students by assessing differences in key sleep parameters between sex and age groups.
View Article and Find Full Text PDFEpidemiologic survey for work-related idiopathic interstitial pneumonias focusing on idiopathic pulmonary fibrosis in Korea, 2010-2022.
J Occup Environ Med
January 2025
Department of Research for Occupational Health, Institute of Occupation and Environment, Korea Workers' compensation & Welfare Service, Incheon, Republic of Korea.
Objective: This study aimed to share the process of epidemiologic survey and demonstrate the decisive factors for evaluating work-related Idiopathic interstitial pneumonias (IIPs) in Korea.
Methods: Data and reports of epidemiologic surveys were investigated and completed during 2010-2022.
Results: A total of 228 idiopathic pulmonary fibrosis (IPF) cases requested for an epidemiologic survey, of which 153 (67.
Increased plugging latency in cycling epiERα-/- (Esr1f/-Wnt7aCre/+) mice.
Reproduction
January 2025
X Ye, Department of Physiology and Pharmacology, University of Georgia, Athens, United States.
Wnt7a-Cre is a commonly used for generating uterine epithelial conditional knockout mice, such as epiERα-/- (Esr1f/-Wnt7aCre/+) and epiPR-/- (Pgrf/-Wnt7aCre/+). We noticed that epiERα-/- females, but not epiPR-/- females, have prolonged plugging latency, which is the duration between continuous cohabitation and detection of the first vaginal plug (a sign of mating). Mating occurs in proestrus and/or estrus stages of the estrous cycle.
View Article and Find Full Text PDFBallet shows numerous physiological benefits for dancers, with adaptations in posture, power, strength, stamina, and balance. The recent study from Simpkins and Yang (2024) showed 45% of ballet-trained dancers experienced a fall during a standing-slip perturbation, compared with 82.6% of non-dancers; along with shorter step latencies, durations, and speeds, which were accompanied by shorter electromyographic latencies in several leg muscles.
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