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Basic self-disturbance in adolescents at risk of psychosis: temporal stability investigated by the experience sampling method in a mixed method study.
BMJ Ment Health
October 2024
Department of Mental Health Research and Development, Vestre Viken Hospital Trust, Drammen, Drammen, Norway.
Background: Basic self-disturbance (BSD), also called anomalous self-experiences (ASEs), are core phenotypic markers for schizophrenia spectrum disorders and a prepsychotic vulnerability marker considered to be temporally stable (trait-phenomenon). Studies of BSD in children and adolescents are lacking.
Objective: To be clinically useful, we need to know more about the characteristics and temporal development of BSD in prepsychotic phases.
Mentalization-based approach for schizophrenia spectrum disorders: a psychotherapeutic proposal for evolved schizophrenic trajectories and serious mental disorders.
Front Psychiatry
May 2024
Instituto de Neuropsiquiatría y Adiciones (INAD), Centro Emili Mira y Hospital del Mar, Parc de Salut Mar, Barcelona, Centro de Investigación en Red de Salud Mental (CIBERSAM), Departamento de Psiquiatría, Universidad Autónoma de Barcelona, EspañaIMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
There is a growing interest in psychotherapeutic approaches to pre-psychotic high-risk states or first-episode psychosis, where mentalization-based treatment has shown its utility. This article presents a mentalization-based approach for the treatment of those individuals diagnosed with an evolved schizophrenia spectrum disorder, whose characteristics make them especially inaccessible to reflective psychotherapeutic treatment. A synthesis of the conceptual frameworks that justify the needs for technical modification of the mentalization-based treatment foundational techniques is carried out, followed by the proposal of adaptations, with a focus in self-agency and patient-therapist dyad.
View Article and Find Full Text PDFPsychopathological mediators between insecure attachment and psychotic features in a non-clinical sample: the role of depression and interpersonal sensitivity.
Riv Psichiatr
July 2023
Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy - IRCSS Fondazione Santa Lucia, Rome, Italy.
Introduction: Attachment styles represent a personality pattern critical to psychological health, with insecure attachment being a central factor in developing psychopathological characteristics of psychosis. However, its downstream psychopathological pathways remain unclear. This study aimed to investigate the putative psychopathological mediators in the relationship between insecure attachment and psychotic features in a non-clinical sample of university students.
View Article and Find Full Text PDFA Bayesian model of psychosis symptom trajectory in Alzheimer's disease.
Int J Geriatr Psychiatry
February 2016
Department of Psychiatry, University of Pittsburgh, PA, USA.
Objective: Psychosis, like other neuropsychiatric symptoms of dementia, has many features that make predictive modeling of its onset difficult. For example, psychosis onset is associated with both the absolute degree of cognitive impairment and the rate of cognitive decline. Moreover, psychotic symptoms, while more likely than not to persist over time within individuals, may remit and recur.
View Article and Find Full Text PDFSleep dysfunction and thalamic abnormalities in adolescents at ultra high-risk for psychosis.
Schizophr Res
December 2013
Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. Electronic address:
Background: Sleep dysfunction is a pervasive, distressing characteristic of psychosis, yet little is known regarding sleep quality prior to illness onset. At present, it is unclear whether sleep dysfunction precedes the emergence of psychotic symptoms, signifying a core feature of the disorder, or if it represents a consequence of prolonged contact with aspects of schizophrenia and its treatment (e.g.
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