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Meta-analysis on the effect of pituitary adenoma resection on pituitary function.
Neurol Neurochir Pol
March 2021
920th Hospital of the Combined Service Force of the Chinese People's Liberation Army, No. 212 Daguan Street, Xishan District, 650032 Kunming, China.
Objective: A meta-analysis was conducted on the effect of pituitary adenoma resection on pituitary function.
Methods: The Cochrane Library, Ovid, PubMed, the Excerpta Medica Database (EMBASE), and the Chinese Biomedical Literature Databases (CBM) were searched to find trials about the evaluation of pituitary target glands before and after pituitary adenoma resection. The databases were searched from the earliest available trials until the end of September 2019.
Anterior panhypopituitarism in diffuse large B-cell stage IV lymphoma.
J Clin Neurosci
August 2014
Division of Endocrinology, Department of Medicine, National University Hospital Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 10, Singapore 119228, Singapore.
The most common presentation of metastases to the pituitary gland in systemic lymphoma is diabetes insipidus resulting from infiltration of the infundibulum/posterior lobe. We describe a 69-year-old man with diffuse large B-cell stage IV lymphoma who presented with anterior pituitary hypofunction, without features of posterior pituitary involvement. He presented with a few months of postural dizziness and hypotension, weight loss, fever, strabismus of right eye and a superficial abdominal wall mass.
View Article and Find Full Text PDFComparison of 68Ga-DOTATOC biodistribution in patients with and without spleenectomy.
Q J Nucl Med Mol Imaging
March 2015
Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Aim: Ga-68 labeled somatostatin analogues such as 68Ga-DOTA0-Phe1-Tyr3-octrotide (DOTATOC) as PET tracers, have significantly improved the imaging of somatostatin receptors (SSTRs) expressing tumors. Due to unspecific parenchymal binding and the expression of SSTRs on leukocytes in the spleen this is the organ with the highest non-tumor uptake of DOTATOC. Therefore, we investigated the potential changes of normal tissue distribution and tumor concentration in patients with neuroendocrine tumors (NETs) with or without spleenectomy.
View Article and Find Full Text PDFHarvey Cushing: Cushing's disease.
J Perioper Pract
September 2012
Department of Anatomy, University of London, Guy's Hospital, Guy's Campus, London SE1 1UL.
In 1932 Harvey Cushing published an article entitled 'Basophil adenomas of the pituitary and their clinical manifestations'. These are rare tumours of the anterior pituitary gland, at the base of the brain, with striking manifestations, which include adiposity of the face and trunk, but not the limbs, weakness, fatigue, abdominal striae, facial hair, high blood pressure and raised blood sugar. Although I spent two years in an army neurosurgical unit, I never saw a case.
View Article and Find Full Text PDFFirst ladies in laying the foundation of neuroendocrinology.
Ir J Med Sci
March 2013
School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland.
Although women were welcomed into medical practice in increasing numbers by the close of the nineteenth century, it was not until the second quarter of the twentieth century that they were recognised as valuable collaborators and contributors in the nascent field of neuroendocrinology, wherein they soon made advances that have stood the test of time. Mary Pickford at Edinburgh measured the action of acetyl choline in the supraoptic nucleus of the hypothalamus and helped to establish that vasopressin and oxytocin are formed in separate and distinct neurons. Berta Scharrer, like her future husband Ernest Scharrer, was born in Munich.
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