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Re-architecture for requirements of academic space development in the universities: design and validitation of RASD questionnaire.
Sci Rep
January 2025
Department of Leadership and Educational management, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.
Universities are the cornerstone of social development and progress; however, it is essential to enhance the academic environment to support this mission. The objective of this research is to identify the Requirements for Academic Space Development (RASD) in universities. The present study was conducted in 2022-2023 using a mixed-method with a qualitative-quantitative sequence.
View Article and Find Full Text PDFComparing four different methods of measuring fracture toughness and its relationship with fractal dimension in a polycrystalline (3Y-TZP) dental ceramic.
Dent Mater
January 2025
Department of Biomedical Materials Science, University of Mississippi Medical Center, 2500 North State Street, Room D528, Jackson, MS 39216-4505, USA. Electronic address:
Objectives: Previous studies reported various methods of measuring fracture toughness of dental ceramics. The objectives of this study were to compare different methods and to validate fractal analysis to estimate fracture toughness for a polycrystalline dental ceramic.
Methods: Bar-shaped specimens were prepared from 3 mol% yttria-stabilized tetragonal polycrystalline (3Y-TZP) ceramic.
Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition.
Drug Metab Dispos
January 2025
Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, United Kingdom; Certara Predictive Technologies, Sheffield, United Kingdom.
The placenta acts as a barrier, excluding noxious substances while actively transferring nutrients to the fetus, mediated by various transporters. This study quantified the expression of key placental transporters in term human placenta (n = 5) and BeWo, BeWo b30, and JEG-3 placenta cell lines. Combining these results with pregnancy physiologically based pharmacokinetic (PBPK) modeling, we demonstrate the utility of proteomic analysis for predicting placental drug disposition and fetal exposure.
View Article and Find Full Text PDFIn-vivo high-resolution χ-separation at 7T.
Neuroimage
January 2025
Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea. Electronic address:
A recently introduced quantitative susceptibility mapping (QSM) technique, χ-separation, offers the capability to separate paramagnetic (χ) and diamagnetic (χ) susceptibility distribution within the brain. In-vivo high-resolution mapping of iron and myelin distribution, estimated by χ-separation, could provide a deeper understanding of brain substructures, assisting the investigation of their functions and alterations. This can be achieved using 7T MRI, which benefits from a high signal-to-noise ratio and susceptibility effects.
View Article and Find Full Text PDFUrban soils immobilize harmful microbes and antibiotic resistance genes.
J Hazard Mater
January 2025
School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Rd., Shanghai 200240, China; Shanghai Yangtze River Delta Eco-Environmental Change and Management Observation and Research Station, Ministry of Science and Technology, Ministry of Education, 800 Dongchuan Rd., Shanghai 200240, China; Shanghai Urban Forest Ecosystem Research Station, National Forestry and Grassland Administration, 800 Dongchuan Rd., Shanghai 200240, China. Electronic address:
Exposure to harmful microbiomes and antibiotic resistance genes (ARGs) can negatively affect human health. However, the contribution of vegetation and soils to the airborne microbiota transferred indoors (AMTI) remains unclear. We used our newly-developed airborne microbial sampler (VenTube) to collect AMTI samples from 72 neighborhoods in Shanghai.
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