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Association between cardiometabolic index and risk of testosterone deficiency in adult men: a cross-sectional study.
BMC Public Health
January 2025
Department of Urology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Background: Metabolic health is closely related to testosterone levels, and the cardiometabolic index (CMI) is a novel metabolic evaluation metric that encompasses obesity and lipid metabolism. However, there is currently a lack of research on the relationship between CMI and testosterone, which is the objective of this study.
Methods: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) cycles from 2011 to 2016.
Targeting mutant p53: Evaluation of novel anti-p53 monoclonal antibodies as diagnostic tools.
Sci Rep
January 2025
Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.
About 50% of all cancers carry a mutation in p53 that impairs its tumor suppressor function. The p53 missense mutation p53 (p53 in mice) is a hotspot mutation in various cancer types. Therefore, monoclonal antibodies selectively targeting clinically relevant mutations like p53 could prove immensely value.
View Article and Find Full Text PDFDetecting Xe in an atmospheric tracer experiment.
J Environ Radioact
January 2025
Nevada National Security Sites, Mercury, Nevada, 89023, USA. Electronic address:
The Xcounts algorithm for calculating air concentrations of radioactive xenon isotopes (Eslinger et al., 2023) has been extended to estimate Xe in addition to Xe, Xe, Xe, and Xe. The algorithm was applied to 119 samples collected with a SAUNA Q system (Ringbom et al.
View Article and Find Full Text PDFImpact of cerium doping on the peroxidase-like activity of metal-organic frameworks.
Dalton Trans
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Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, Frontiers Science Center for Rare Isotopes, College of Chemistry and Chemical Engineering, Lanzhou University, 73000 Lanzhou, China.
Hydrogen peroxide, phenols, amines, aldehydes, and other substances can easily damage intracellular biomacromolecules. Although natural peroxidases can convert these harmful substances into benign ones, the high costs, poor stabilities, and stringent application conditions associated with these enzymes necessitate the exploration of artificial mimics. In this study, Ce-doped MIL-101(Fe)-NH and MIL-101(Fe)-NO were synthesized with varying compositions a solvothermal method.
View Article and Find Full Text PDFDiagnostic delay among symptomatic breast cancer patients: a study in Sudanese women.
J Prev Med Hyg
September 2024
Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Background: Early diagnosis of breast cancer is essential for effective treatment and improved survival rates. A longer gap between the appearance of symptoms and the initiation of therapy results in advanced disease and lower survival.Objectives: to assess factors associated with diagnosis delay among Sudanese women with breast cancer.
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