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[The infection theory in atherosclerosis].
Arch Mal Coeur Vaiss
October 1998
Service de médecine interne, Hôtel-Dieu, Paris.
Atherosclerosis displays all the features of a chronic inflammatory process. Aggressions that ignite and fuel atherosclerotic inflammation warrant keen attention. Infection is a potential clue, implying microbes with certain discrete characteristics: a wide epidemiologic distribution, a tropism for the arterial wall, and an aptitude for persistence, latency and recurrence.
View Article and Find Full Text PDFThe Snow Mountain Agent (SMA) is a Norwalk-like viral agent of acute gastroenteritis that has been detected only by immune electron microscopy (IEM). We established a solid phase microtiter radioimmunoassay (RIA) for SMA antigen employing pre-and post-challenge sera from volunteer studies as capture antibodies. SMA was detected in 12 of 67 stool samples from volunteers who were ill after oral challenge with SMA.
View Article and Find Full Text PDFSero-epidemiology of herpes type-2 virus and carcinoma of the cervix in Ibadan.
Afr J Med Med Sci
June 1977
Various sero-epidemiologic studies, including the preliminary report from Ibadan, have established that most women with premalignant and malignant carcinoma of the cervix have serologic evidence of infection of herpes type-2 virus. Using immunofluorescence method, the earlier report in Ibadan was confirmed, whereby the prevalence of HT-2 virus antibodies was shown to be significantly associated with carcinoma of the cervix, especially the squamous cell type. However, there was no such association with the grade and stage of the disease.
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