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Exercise offers a plethora of health benefits. However, certain genetic and acquired diseases such as cardiomyopathies and channelopathies are associated with sudden cardiac death during exercise. Several factors complicate exercise prescription in individuals living with these conditions.

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Seasonal variation of unexpected sudden cardiac death in northern Finland.

Cardiovasc Pathol

January 2025

Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland. Electronic address:

Background: Data on the occurrence of unexpected sudden cardiac death (SCD) in different seasons are limited.

Methods: All unexpected sudden death victims have to undergo medico-legal autopsy obligated by the Finnish law. Consecutive series of all unexpected autopsied SCD victims (n=5,869) were prospectively collected from the geographically defined area in the Northern Finland during a twenty years period from 1998 to 2017.

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Healthcare Utilization One Year Before Sudden Cardiac Death in Taiwan.

Am J Prev Med

January 2025

Department of Emergency Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan; Department of Emergency Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:

Introduction: This study aimed to investigate the patterns of healthcare system utilization before sudden cardiac death (SCD) in Taiwan, and compare the patterns between patients treated at medical centers and non-center hospitals.

Methods: This descriptive multicenter retrospective cohort study recruited adult, nontraumatic SCD patients who were admitted to the National Taiwan University Hospital and its affiliated hospitals between January 2017 and December 2022. Healthcare utilization patterns, such as outpatient visits, emergency department (ED) visits, short-term ED returns, and hospitalizations, were analyzed during the weeks prior to SCD.

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Sudden Cardiac Death: Insights From Transcriptomics.

JACC Clin Electrophysiol

January 2025

Division of Cardiology, Department of Medicine, University of California-Los Angeles, Los Angeles, California, USA; UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine, UCLA, Los Angeles, California, USA; Neurocardiology Research Program of Excellence, David Geffen School of Medicine, UCLA, Los Angeles, California, USA; Center for Interventional Programs, UCLA Health System, Los Angeles, California, USA. Electronic address:

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Vascular calcification(VC) significantly increases the risk of cardiovascular events, leading to thickening of the myocardium and arteries, coronary heart disease, heart failure, and potentially triggering myocardial infarction and sudden cardiac death. Although VC is a reversible process, there are currently no methods or medications in clinical practice that can completely reverse or cure it. The current treatment strategies primarily focus on slowing the progression of VC and exploring new diagnostic and therapeutic approaches, making the identification of early diagnostic markers for VC particularly important.

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