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Pulmonary hypertension is characterized by higher-than-normal pulmonary arterial pressures. This case report describes the perioperative management of a male patient with idiopathic pulmonary hypertension and a history of vasovagal syncope during previous dental extractions with local anesthesia. He underwent successful extraction of a single tooth with intravenous moderate sedation using dexmedetomidine and midazolam as well as prilocaine with felypressin for local anesthesia.
View Article and Find Full Text PDFEffect of local anesthetics on renal function: An animal study in Iran.
Dent Res J (Isfahan)
October 2023
Postgraduate Student, Dental Students' Research Committee, Department of Endodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Although most of the metabolism of local anesthetics (LAs) takes place in the liver, no study has investigated the effect of these anesthetics on the kidney function of single-kidney humans or animals. The present study was conducted to examine the effect of LAs on renal function in single-kidney rats.
Materials And Methods: The present experimental animal study with two control groups was done in an animal laboratory.
Methemoglobinemia Induced by Prilocaine in a Child With Noonan Syndrome.
Anesth Prog
September 2022
Division of Dental Anesthesiology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan.
Limited information is currently available on methemoglobinemia caused by the administration of prilocaine in children undergoing dental procedures in Japan. This case report presents the development of methemoglobinemia due to prilocaine overdose. The patient was a female aged 5 years 8 months with Noonan syndrome who also had pulmonary valve stenosis and hypertrophic cardiomyopathy.
View Article and Find Full Text PDFPatient Comfort with Various Local Infiltration Anesthetics for Minor Oculoplastic Surgery: A Systematic Review and Network Meta-Analysis.
J Plast Reconstr Aesthet Surg
September 2022
Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan; Division of Plastic Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University; Evidence-Based Medicine Center, Wan Fang Hospital, Taipei Medical University, Taiwan; Cochrane Taiwan, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, Taiwan. Electronic address:
Background: Although local anesthetics have been extensively studied, limited evidence is available regarding the optimal solution for maximizing patient comfort in minor oculoplastic procedures.
Objectives: To determine the optimal anesthetic solution for local infiltration in minor oculoplastic surgeries to maximize patient comfort.
Methods: This systematic review with network meta-analysis of prospective studies was conducted to understand the efficacy of different local anesthetics in combination to maximize patient comfort.
Comparison of the Anaesthesia Success Rate in Maxillary First and Second Molars with 3% Prilocaine as the Anaesthetic Agent.
Eur Endod J
December 2021
Department of Oral Restorative and Rehabilitative Sciences, Faculty of Dentistry, University of Western Australia, Perth, Australia.
Objective: The aim of this study was to compare the success rate of anaesthesia with 3% prilocaine and felypressin (0.03 IU/mL) in maxillary first and second molar teeth with irreversible pulpitis.
Methods: The study population was 159 patients (53 males, 106 females) who had maxillary first or second molar teeth with irreversible pulpitis (84 first molars, 75 second molars).
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