Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Antibiotic Prescription Practice and Resistance Patterns of Bacterial Isolates from a Neonatal Intensive Care Unit: A Retrospective Study from Jordan.
Antibiotics (Basel)
January 2025
Pharmacy and Clinical Pharmacy Directorate, Ministry of Health, Amman 11941, Jordan.
: Neonatal sepsis is a systemic inflammation in neonates caused by bacteria, viruses, or fungi that can progress into severe conditions. In developing countries, neonatal sepsis is a major cause of mortality and a major public health issue with a high prevalence. This study aims to evaluate the antibiotic prescription practice and resistance patterns of bacterial isolates from the neonatal intensive care unit (NICU) at the largest governmental hospital in Amman, Jordan.
View Article and Find Full Text PDFExploring in vitro efficacy of rCHAPk with antibiotic combinations, and promising findings of its therapeutic potential for clinical-originated MRSA wound infection.
Int J Biol Macromol
January 2025
Yıldız Technical University, Faculty of Science and Arts, Department of Molecular Biology and Genetics, Istanbul, Turkey. Electronic address:
The increasing threat of antimicrobial-resistant bacteria, particularly Staphylococcus aureus, which rapidly develops multidrug resistance and commonly colonizes wound surfaces, demands innovative strategies. Phage-encoded endolysins offer a dual-purpose approach as topical therapies for infectious skin wounds and synergistic agents to reduce high-dose antibiotic dependence. This study explores recombinant CHAPk (rCHAPk), efficiently synthesized within 3 h, displaying broad-spectrum antibacterial activity against 10 Gram-positive strains, including resistant variants, with rapid bactericidal kinetics.
View Article and Find Full Text PDFMedication Hazards and Outcome Patterns of Pediatric Drug-Associated Liver Injury in Taiwan: An Analysis of 1998-2017 Spontaneous Adverse Drug Reaction Reports.
Drugs Real World Outcomes
January 2025
School of Pharmacy, College of Medicine, National Taiwan University, Taipei, 100025, Taiwan.
Background And Objectives: Accumulating pediatric efficacy and safety data on drug use is inherently challenging yet essential. This study aimed to analyze the frequency and compute the odds of pediatric drug-associated liver injury across age groups (early childhood, middle childhood, and adolescence) and therapeutic categories using adverse drug reactions (ADRs) reporting data spanning nearly two decades.
Methods: We analyzed the reports of suspected ADRs occurring in children and adolescents in the Taiwan National Adverse Drug Reaction Reporting System during the period from May 1998 until July 2017.
Discordant β-Lactam Susceptibility in Clinical Isolates: A Molecular and Phenotypical Exploration to Detect the BORSA/MODSA Isolates in Bogotá, Colombia.
Microorganisms
December 2024
Grupo de Investigación Celular y Molecular de Microorganismos Patógenos, Department of Biological Scieces, Universidad de los Andes, Bogotá 111711, Colombia.
is a human pathogen responsible for a wide range of diseases, such as skin and soft tissue infections, pneumonia, toxic shock syndrome, and urinary tract infections. Methicillin-resistant (MRSA) is a well-known pathogen with consistently high mortality rates. Detecting the resistance gene and phenotypical profile to β-lactams allows for the differentiation of MRSA from methicillin-susceptible (MSSA) isolates.
View Article and Find Full Text PDFCurrent status of the distribution and antimicrobial resistance of Staphylococcus felis isolates from feline patients in Japan.
J Vet Med Sci
January 2025
Laboratory of Veterinary Internal Medicine, Tottori University.
We investigated the distribution and antimicrobial resistance of 120 Staphylococcus felis isolates from feline patients in Japan, mainly from the urinary tract (28.3%), abscesses (23.3%), ears (22.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!