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Shorter and inflexible intrinsic neural timescales of the self in schizophrenia.
J Psychiatry Neurosci
January 2025
From the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Djimbouon); the Mind, Brain Imaging and Neuroethics Unit, Institute of Mental Health Research, Royal Ottawa Mental Health Centre, University of Ottawa, Ottawa, Ont. (Djimbouon, Northoff); the Faculty of Mathematics and Natural Sciences, Institute of Experimental Psychology, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany (Klar); and the Institute of Neuroscience and Medicine, Brain & Behaviour (INM-7), Research Centre Jülich, Jülich, Germany (Klar).
Background: Schizophrenia is hypothesized to involve a disturbance in the temporal dynamics of self-processing, specifically within the interoceptive, exteroceptive, and cognitive layers of the self. This study aimed to investigate the intrinsic neural timescales (INTs) within these self-processing layers among people with schizophrenia.
Methods: We conducted a functional magnetic resonance imaging (fMRI) study to investigate INTs, as measured by the autocorrelation window, among people with schizophrenia and healthy controls during both resting-state and task (memory encoding and retrieval) conditions.
MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
PLoS One
January 2025
Department of Psychology, Muslim Youth University, Islamabad, Pakistan.
Parental history of schizophrenia, a complex and multifaceted psychological disorder, is recognized as a well-established risk factor in the development of the disorder among offspring. However, the developmental patterns of such children and adolescents before the onset of the problem have not yet been systematically documented. We present a comprehensive account of developmental checkpoints essential for preventing it from occurring.
View Article and Find Full Text PDFAffective predictors of social support in individuals with schizophrenia.
Schizophr Res
January 2025
Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, United States of America.
Background: Social Support has been found to contribute to lower mental illness burden, higher treatment adherence, enhanced social functioning, and better quality of life. Individuals with schizophrenia report lower social support compared to non-clinical populations, yet the factors contributing to this discrepancy are not fully clear. Specifically, the person-related variables that may enhance or hinder SS in people with schizophrenia are unknown.
View Article and Find Full Text PDFCultural Beliefs About the Etiology of Schizophrenia and Expressed Emotion in Mexican Families.
Rev Colomb Psiquiatr (Engl Ed)
December 2024
Instituto Mexicano del Seguro Social, Social and Epidemiological Research Unity of Mexican Institute of Social Security (UISESS-IMSS), Guadalajara, Jalisco, México.
Introduction: Schizophrenia is a severe and persistent mental disorder that affects around 21 million people worldwide. The etiology of schizophrenia is currently understood as heterogeneous and multifactorial. Genetic and environmental factors are the most common explanations for the onset of schizophrenia, but along with these, hybridized cultural ideas coexist between medical, superstitious, and religious paradigms.
View Article and Find Full Text PDFDisentangling the topological symptom structure of schizophrenia: A network analysis.
Schizophr Res
January 2025
Department of Psychiatry, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan International Joint Laboratory of Biological Psychiatry, Zhengzhou University, Zhengzhou, China; Henan Psychiatric Transformation Research Key Laboratory, Zhengzhou University, Zhengzhou, China. Electronic address:
Background And Hypothesis: The Positive and Negative Syndrome Scale (PANSS), comprehensively assesses schizophrenia severity. While network analyses of schizophrenic symptoms have yielded inconsistent results, components of disorganized thought consistently rank high in centrality. The present study aims to explore the centrality of disorganized thought across patient subgroups and its potential as a treatment target.
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