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Rapid and dual-mode nitrite detection with improved sensitivity by nanointerface-regulated ultrafast Griess assay.
Anal Chim Acta
January 2025
College of Chemistry, Beijing University of Chemical Technology, Beijing, 100029, China. Electronic address:
Background: The rapid and sensitive detection of nitrite is important to human health protection due to its carcinogenic and teratogenic risks with excessive intake. The Griess assay is widely applied for the design of nitrite detection system. However, its relatively slow reaction kinetics and sole colorimetry mode might limit it's the sensitivity and practical application.
View Article and Find Full Text PDFAssociation of NOS2A Gene Polymorphisms with Susceptibility to Tuberculosis in Manipuri Population of Northeast India.
Biochem Genet
January 2025
Department of Biotechnology, Manipur University, Canchipur, Imphal, 795003, Manipur, India.
Single nucleotide polymorphisms (SNPs) have been reported to influence the activity of specific genes involved with the innate immune response to Mycobacterium; hence, they are crucial in tuberculosis (TB) susceptibility studies. The study aimed to investigate the polymorphism in the NOS2A (Nitric oxide synthase 2A) gene and its association with susceptibility to TB in the Manipuri population of northeast India. This case-control study includes 495 subjects- 220 TB patients and 275 control individuals.
View Article and Find Full Text PDFpH-Dependent Electrocatalytic Aqueous Ammonia Oxidation to Nitrite and Nitrate by a Copper(II) Complex with an Oxidation-Resistant Ligand.
J Am Chem Soc
January 2025
Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520, United States.
The electrocatalytic aqueous ammonia oxidation (AO) represents a more sustainable alternative to accessing nitrite (NO) and nitrate (NO). We now report that Cu(pyalk) {pyalk = 2-(pyridin-2-yl)propan-2-oate}, previously employed as a homogeneous water oxidation (WO) catalyst, is also active for selective AO in aqueous environments. The traditional Griess analytical test for NO/NO was modified to permit the operation in the presence of the otherwise interfering Cu ion.
View Article and Find Full Text PDFHimalaflavones F and G, two new flavonoids from the roots of Edgew with anti-inflammatory activity.
Nat Prod Res
December 2024
Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. China.
Himalaflavones F () and G (), two new flavonoids, along with eight known ones ()were isolated from the roots of Edgew. The chemical structures of these compounds were elucidated by 1D/2D NMR, UV and HR-ESI-ME data. Meanwhile, the anti-inflammatory activities of all isolates were test by using Griess method.
View Article and Find Full Text PDFNear-infrared light-activated nanosystem endows scaffold with controllable nitric oxide release for peripheral nerve regeneration.
J Colloid Interface Sci
November 2024
Jiangxi Provincial Key Laboratory of Additive Manufacturing of Implantable Medical Device, Jiangxi University of Science and Technology, Nanchang 330013, China; State Key Laboratory of Precision Manufacturing for Extreme Service Performance, College of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China. Electronic address:
The photosensitive S-nitrosocysteine (CysNO) could respond to light irradiation to produce nitric oxide (NO), exhibiting tremendous potential in accelerating peripheral nerve regeneration. However, its further application was limited by the burst release of NO and the requirement for ultraviolet excitation with low tissue penetration. Herein, a near-infrared-triggered NO controlled release nanosystem UCNP@ZIF-8/CysNO consisting of an upconversion nanoparticle (UCNP) core and zeolitic imidazolate framework-8 (ZIF-8) shell loading with CysNO was constructed, and then blended with poly-l-lactic acid powder to fabricate nerve scaffold by laser additive manufacturing technique.
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