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treatment outcomes among a cohort failing macrolide resistance-guided treatment across three London sexual health clinics.
Sex Transm Infect
August 2024
Directorate of Sexual Health and HIV Medicine, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
Objective: British guidelines advise treatment of () infection using the results of macrolide resistance-associated mutation (MRAM) assays. Limited data informs management when patients fail MRAM-guided treatment. This study evaluates current management strategies employed for cases of infection with MRAM-guided treatment failure.
View Article and Find Full Text PDFAnalysis of Ureaplasma urealyticum, Chlamydia trachomatis, Mycoplasma genitalium and Neisseria gonorrhoeae infections among obstetrics and gynecological outpatients in southwest China: a retrospective study.
BMC Infect Dis
March 2022
Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, People's Republic of China.
Background: The aim of this study was to analyze the present situation of Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), Mycoplasma genitalium (MG) and Neisseria gonorrhoeae (NG) infections among obstetrics and gynecological outpatients in southwest China.
Methods: A total of 3225 urogenital swabs were included in this study. All swabs were tested by RNA-based simultaneous amplification and testing (SAT) methods.
infections: current treatment options and resistance issues.
Infect Drug Resist
September 2017
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
is one of the important causes of non-gonococcal urethritis. Rising incidence and emerging antimicrobial resistance are a major concern these days. The poor clinical outcomes with doxycycline therapy led to the use of azithromycin as the primary drug of choice.
View Article and Find Full Text PDFNew Horizons in Mycoplasma genitalium Treatment.
J Infect Dis
July 2017
Department of Pathology, University of Alabama at Birmingham.
Mycoplasmagenitalium is an important sexually transmitted pathogen responsible for both male and female genital tract disease. Appreciation of its significance in human disease has been hampered by its slow growth in culture, difficulty in isolating it, and lack of commercial molecular-based tests for rapid detection. Comparatively few in vitro data on antimicrobial susceptibility are available due to the scarcity of clinical isolates and difficulty in performing susceptibility tests to determine minimum inhibitory concentrations for M.
View Article and Find Full Text PDFManaging community acquired pneumonia in the elderly - the next generation of pharmacotherapy on the horizon.
Expert Opin Pharmacother
August 2017
a Department of Medicine, Division of Pulmonary and Critical Care Medicine , University of Texas Health Science Center San Antonio, San Antonio , TX , USA.
Community acquired pneumonia (CAP) is associated with high rates of morbidity and mortality, especially among the elderly. Antibiotic treatment for CAP in the elderly is particularly challenging for many reasons, including compliance issues, immunosuppression, polypharmacy and antimicrobial resistance. There are few available antibiotics that are able to address these concerns.
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