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Synergistic effects of reduced graphene oxide on the antibacterial activity of calcium hydroxide-based intracanal medicaments containing different vehicles.
J Oral Sci
January 2025
Department of Conservative Dentistry, School of Dentistry and Institute of Oral Bioscience, Jeonbuk National University.
Purpose: This study investigated the synergistic effects of reduced graphene oxide (RGO) on the antibacterial activity of three calcium hydroxide-based intracanal medicaments with different vehicles.
Methods: Multispecies biofilms were cultured in a bovine root canal model. Intracanal medicaments containing nonaqueous vehicles, including N-methyl-2-pyrrolidone (NMP; CleaniCal), propylene glycol (PG; UltraCal XS), and polyethylene glycol (PEG; Calcipex II), were placed in the model.
A metabolic switch to the pentose-phosphate pathway induces radiation resistance in pancreatic cancer.
Radiother Oncol
January 2025
The Benjamin Davidai Department of Radiation Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel; Tel-Aviv University, Chaim Levanon St. 55, Tel Aviv-Yafo 6997801, Israel; Sidney Kimmel Medical College at Thomas Jefferson University, 4201 Henry Ave, Philadelphia, PA 19144, USA. Electronic address:
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is remarkably resistant to standard modalities, including radiotherapy. We hypothesized that metabolic reprogramming may underlie PDAC radioresistance, and moreover, that it would be possible to exploit these metabolic changes for therapeutic intent.
Methods And Materials: We established two matched models of radioresistant PDAC cells by exposing the AsPC-1 and MIAPaCa-2 human pancreatic cancer cells to incremental doses of radiation.
An ultrasensitive free-of-electronic sacrificial agent photoelectrochemical aptasensor for the detection of dibutyl phthalate based on Z-scheme p-n Bi-doped BiOI/BiS heterojunction.
Talanta
January 2025
College of Energy Environment and Safety Engineering & College of Carbon Metrology, China Jiliang University, Hangzhou, Zhejiang, 310018, PR China; Institute of Environmental and Health Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, PR China. Electronic address:
Article Synopsis
- Dibutyl phthalate (DBP) is a harmful plasticizer with properties that can disrupt hormones, cause genetic mutations, and negatively impact health, prompting the need for effective detection methods.
- A novel photoelectrochemical aptasensor was developed using a unique Z-scheme Bi-doped BiOI/BiS composite, improving the sensor’s efficiency in absorbing light and transferring charge.
- This aptasensor showed a wide detection range (2-500 pM) and a low detection limit (0.184 pM), making it highly selective for DBP detection in real water samples without interference from electronic sacrificial agents.
Co-occurrence of mycotoxins in stored maize from southern and southwestern Ethiopia.
Food Addit Contam Part B Surveill
September 2024
School of Plant and Horticultural Sciences, Hawassa University, Hawassa, Ethiopia.
Maize grain samples collected from 129 small-scale farmers' stores in southern and southwestern Ethiopia were analysed by LC-MS/MS for a total of 218 mycotoxins and other fungal metabolites of which 15% were regulated mycotoxins. Mycotoxins produced by , , and accounted for 31%, 17%, and 12% of the metabolites, respectively. Most of the current samples were contaminated by masked and/or emerging mycotoxins with moniliformin being the most prevalent one, contaminating 93% of the samples.
View Article and Find Full Text PDFHighly efficient and sensitive detection of tetracycline in environmental water: Insights into the synergistic mechanism of biomass-derived carbon dots and N-methyl pyrrolidone solvent.
Talanta
October 2024
School of Ecological and Environmental Sciences, Shanghai Engineering Research Center of Biotransformation of Organic Solid Waste, Shanghai Key Lab for Urban Ecological Processes and Eco-Restoration, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China; Institute of Eco-Chongming (IEC), 3663 North Zhongshan Road, Shanghai, 20062, China. Electronic address:
Article Synopsis
- Tetracycline (TC) contamination in water poses serious public health risks, making its detection crucial for environmental safety.
- The study utilized nitrogen-doped carbon dots (N-CDs) derived from Ophiopogon japonicus for TC sensing, demonstrating that a unique solvent mixture significantly improved detection sensitivity through a combination of fluorescence quenching and enhancement.
- This method achieved a low detection limit of 6.3 nM within 60 seconds, showcasing the potential for low-cost, stable biomass materials in developing effective environmental sensors.
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