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Cavo-portal transposition in rat: a new simple model.
BMC Surg
August 2007
Department of General Surgery and Organ Transplantation, S. Martino Hospital, Genoa, Italy.
Background: Liver transplantation in presence of diffuse portal vein thrombosis is possible by using caval blood as portal inflow, through cavo-portal transposition. However, clinical results are heterogeneous and experimental studies are needed, but similar hemodynamic conditions are difficult to obtain, especially in small animals. Herein we describe a new simple model of cavo-portal transposition in rat.
View Article and Find Full Text PDFLiver transplantation using cavoportal transposition: an effective treatment in patients with complete splanchnic venous thrombosis.
Transplant Proc
March 2005
Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.
Complete venous thrombosis of the splanchnic system remains a major challenge in liver transplantation surgery. Some of these patients have been treated successfully by multivisceral transplantation. Cavoportal transposition is another alternative to treat these patients.
View Article and Find Full Text PDFLung injury from gut ischemia: insensitivity to portal blood flow diversion.
J Trauma
October 1993
Department of Surgery, University of Texas Medical School at Houston 77030.
Gut ischemia/reperfusion (I/R) appears to produce pulmonary vascular injury through endotoxin release and cytokine activation. The ability of hepatic reticuloendothelial cells to clear bacterial products may also be impaired during I/R. To test this, diversion of the splanchnic blood flow from the liver into the systemic circulation was performed via a microsurgical portacaval transposition in anesthetized Sprague-Dawley rats (275-375 g).
View Article and Find Full Text PDF[Hyperestrogenemia following various shunt operations: on the role of estrogens in the development of focal nodular hyperplasia of the liver].
Z Gastroenterol
July 1989
Medizinische Klinik, Recklinghausen.
Hormones especially estrogens have been suspected to induce liver cell tumours or hepatic focal nodular hyperplasia (FNH). In rats 6 months after portocaval anastomosis (PCA) the occurrence of FNH has been observed. Modified portocaval anastomosis (mPCA) does not lead to FNH.
View Article and Find Full Text PDFThree methods of measuring hepatic first-pass metabolism of salicylamide in dogs that had undergone portacaval transposition were compared. The drug in both its radiolabeled (0.74 MBq) and unlabeled (20 mg/kg) forms was infused concurrently into forelimb and hindlimb veins, respectively.
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