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Parasitol Res
January 2025
Department of Medical Biology, Faculty of Science, University of South Bohemia, Branišovská 1760, CZ-37005, České Budějovice, Czech Republic.
Tick-borne encephalitis virus (TBEV) is flavivirus transmitted to the host via tick saliva which contains various molecules with biological impacts. One of such molecules is Iristatin, a cysteine protease inhibitor from Ixodes ricinus that has been shown to have immunomodulatory properties. To characterize Iristatin in the relation to TBEV, we investigate whether this tick inhibitor has any capacity to influence TBEV infection.
View Article and Find Full Text PDFAnalyst
January 2025
Department of Proteomics, Mass Spectrometry Laboratory, Center for Genetic Engineering and Biotechnology, 31 Avenue, Cubanacan, Playa, Havana, Cuba.
Keyhole limpet haemocyanins (KLH1 and KLH2) from , are multi-subunit oxygen-carrying metalloproteins of approximately 3900 amino acids, that are widely used as carrier proteins in conjugate vaccines and in immunotherapy. KLHs and their derived conjugate vaccines are poorly characterized by LC-MS/MS due to their very stable supramolecular structures with megadalton molecular mass, and their resistance to efficient digestion with standard protocols. KLH1 and KLH2 proteins were conjugated to the conserved P0 peptide (pP0), derived from the P0 acidic ribosomal protein of sp.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Centro di Referenza Nazionale per Anaplasma, Babesia Rickettsia, Theileria (C.R.A.Ba.R.T.), Istituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", 90129 Palermo, Italy.
Ticks are a major concern for both animal and human health, as they are primary vectors of infectious pathogens. This study focused on ticks found in a nature reserve in southern Italy, highly frequented for recreational activities and inhabited by wild boars. Using molecular techniques, 214 ticks, including questing ticks and those removed from wild boars, were examined for tick-borne pathogens (TBPs), with a focus on zoonotic pathogens.
View Article and Find Full Text PDFActa Trop
January 2025
Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), 83304 Hermosillo, Sonora, Mexico. Electronic address:
Front Cell Infect Microbiol
December 2024
Institute of Zoology, Slovak Academy of Sciences, Bratislava, Slovakia.
Introduction: In Europe sensu lato (s.l.), the causative agent of Lyme borreliosis is transmitted by the castor bean tick, .
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