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Obesity substantially impacts rheumatic and musculoskeletal diseases: time to act.
Ann Rheum Dis
March 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Obesity is a major health problem and risk factor for many chronic health conditions, including rheumatic and musculoskeletal diseases (RMDs). Around 7 in 10 adults with RMD live overweight or with obesity. Obesity not only increases the risk of developing RMDs.
View Article and Find Full Text PDFCurrent research status on the structure, physicochemical properties, bioactivities, and mechanism of soybean-derived bioactive peptide lunasin.
Food Chem
March 2025
Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China; Chengdu Agricultural College, Chengdu, Sichuan 611130, China. Electronic address:
Since the 21st century, chronic diseases have become a worldwide health problem due to their high morbidity and mortality. Soybean bioactive substances, especially soybean peptides, are considered to have health benefits beyond nutritional effects. As the most studied peptide in soybean, lunasin has been proven to exert beneficial effects on various chronic disorders.
View Article and Find Full Text PDFBackground: Prolonged symptoms have been reported following both COVID-19 infection and vaccination, with some cases leading to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Of 80 patients presenting to our hospital with postvaccination syndrome, 28 met the diagnostic criteria for ME/CFS. We conducted a retrospective study on these 28 patients.
View Article and Find Full Text PDFChronic postsurgical pain in the ICD-11: implications for anaesthesiology and pain medicine.
Br J Anaesth
March 2025
Division of Clinical Psychology and Psychological Intervention, Institute of Psychology, University of Duisburg-Essen, Essen, Germany.
Chronic postsurgical pain (CPSP) is associated with reduced health-related quality of life and disability. In some patients, it can result in long-term opioid use even after minor surgery. Epidemiological studies have reported highly varying rates of CPSP, largely because researchers have used different definitions with self-defined cut-offs for pain scores.
View Article and Find Full Text PDFComprehensive geriatric assessment for frail older people with chronic kidney disease to increase attainment of patient-identified goals: Statistical analysis plan for a cluster-randomised controlled trial.
Contemp Clin Trials
March 2025
School of Public Health and Preventative Medicine, Monash University, 553 St Kilda Road, Melbourne, Victoria, Australia. Electronic address:
Background: Frailty is highly prevalent in older people with chronic kidney disease (CKD) and associated with more complex healthcare needs. As part of person-centred care, healthcare planning should be tailored to the individual's needs and their desired outcomes. Comprehensive Geriatric Assessment (CGA) is an intervention which can help facilitate this by identifying a person's medical, functional, and psychosocial problems, and then tailoring a coordinated, targeted management plan.
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