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Article Synopsis
  • * She had a splenectomy to address her thrombocytopenia caused by an enlarged spleen (hypersplenism), but nine months later, she experienced exertional dyspnea and was diagnosed with portopulmonary hypertension (PoPH).
  • * Treatment with the medication macitentan improved her symptoms and right heart pressure readings, marking a rare case of PoPH arising after splenectomy.
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Article Synopsis
  • The case describes a rare portal vein (PV) anomaly during embryonic development, specifically highlighting the presence of three distinct portal veins identified through CT venography.
  • The anatomical structure involves the superior and inferior mesenteric veins forming a trunk that splits into one vein entering the liver and another joining the splenic vein, which further divides into two branches entering the liver.
  • This report emphasizes the significance of understanding PV anatomy for surgical planning, as such duplications are extremely rare and can inform better clinical practices among healthcare professionals.
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Abernethy syndrome is a rare congenital vascular anomaly. In this condition, blood from the portal system is diverted to the caval system through a portocaval shunt, entirely or partially bypassing the liver. Prevalence figures in the literature range from 1 per 30000 population up to 1 per 50000 population.

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Four-dimensional Flow MRI-based Computational Fluid Dynamics Simulation for Noninvasive Portosystemic Pressure Gradient Assessment in Patients with Cirrhosis and Transjugular Intrahepatic Portosystemic Shunt.

Radiology

October 2024

From the Department of Diagnostic and Interventional Radiology and Nuclear Medicine (C.R., A.L., I.R., G.A., B.P.S., P.B.) and I. Department of Medicine (F.P., J.K.), University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany; Institute of Multiphase Flows, Hamburg University of Technology, Hamburg, Germany (M.H., M.I., M.S.); and Departments of Radiology, Medical Physics, Biomedical Engineering, Medicine, and Emergency Medicine, University of Wisconsin-Madison, Madison, Wis (S.B.R.).

Background Transjugular intrahepatic portosystemic shunt (TIPS) dysfunction in patients with liver cirrhosis and recurrent symptoms of portal hypertension is primarily assessed with US and confirmed with invasive catheter venography, which can be used to measure the portosystemic pressure gradient (PSPG) to identify TIPS-refractory portal hypertension. To avoid the risks and costs of invasive catheter venography, noninvasive PSPG evaluation strategies are needed. Purpose To demonstrate the feasibility of the combination of four-dimensional (4D) flow MRI with computational fluid dynamics (CFD) for noninvasive PSPG assessment in participants with cirrhosis and TIPS.

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Hepatic Capsular Rupture during Wedged Portography.

J Vasc Interv Radiol

October 2024

Division of Vascular and Interventional Radiology, Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address:

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