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Shear bond strength evaluation of bioactive restorative materials on pretreated carious dentin-influence on silver diamine fluoride, potassium iodide, and glutathione.
J Conserv Dent Endod
November 2024
Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.
Background: Silver diamine fluoride (SDF) has gained popularity for its caries-arresting properties, yet its tendency to cause esthetic concerns due to black-staining limits its widespread acceptance.
Aim: The aim of the study was to evaluate and compare the shear bond strength of Activa BioActive and Giomer restorative material with different protocols of SDF pretreatment on carious dentin.
Materials And Methods: Ninety-two extracted teeth were decoronated at the cementoenamel junction, sectioned 1 mm into dentin, mounted in acrylic resin and randomly divided into four ( = 8) control and six ( = 10) experimental groups.
PLGA Conical Nail Fixation for Acetabular Chondrolabral Delamination in Femoroacetabular Impingement Promotes Cartilage and Labrum Regeneration in a Porcine Model.
Am J Sports Med
January 2025
Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China.
Article Synopsis
- Acetabular chondrolabral delamination (ACD) is a prevalent hip injury with few effective treatments; this study explored the use of PLGA conical nail fixation as a potential method.
- The experiment involved 24 pigs with surgically induced ACD, divided into three groups: a control (no treatment), an acute fixation group using PLGA nails, and a chronic fixation group using spacers before PLGA nails.
- Results indicated that the pigs in the acute fixation group showed significantly better cartilage regeneration and proteoglycan deposition compared to the control and chronic groups, suggesting PLGA nails are effective for treating ACD.
NFATc1 fosters allergic contact dermatitis responses by enhancing the induction of IL-17-producing CD8 cells.
J Invest Dermatol
December 2024
Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany. Electronic address:
A plethora of data supports a major role of CD4 and CD8 T lymphocytes for the initiation, progression and maintenance of allergic contact dermatitis (ACD). However, in-depth understanding of the molecular mechanisms is still limited. NFATc1 plays an essential role in T cell activation.
View Article and Find Full Text PDFAdjustment of the GRACE Score and SHAP Analysis in STEMI Patients.
Comput Methods Programs Biomed
December 2024
College of Mathematics, Taiyuan University of Technology, Taiyuan, Shanxi 030024, PR China. Electronic address:
Background: The GRACE (Global Registry of Acute Coronary Events) risk score is a well-established tool for predicting major cardiovascular events in patients with acute coronary syndrome. However, its application in acute ST-segment elevation myocardial infarction (STEMI) requires refinement to enhance its predictive accuracy in clinical settings.
Methods: In this study, we conducted a retrospective analysis of the incidence of out-of-hospital all-cause death (ACD), calculated the correlation and significance of the GRACE score indicators with ACD, and reduced the scores corresponding to insignificant and low-correlation indicators to adjust the scores for survive patients.
Long-Term Observations on the European Photopatch Test Baseline Series (EPTBS) in Real Clinical Practice: 11 Years of Results in a Spanish Cohort and Suggestions for an EPTBS Update.
Contact Dermatitis
December 2024
Department of Dermatology, Hospital Clínic de Barcelona, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain.
Background: The European Photopatch Testing Baseline Series (EPTBS) was published in 2013. However, limited data exist regarding the real-world clinical application of the EPTBS.
Objectives: This study aims to describe the photopatch test experience with the EPTBS over 11 years at a tertiary hospital in Spain.
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