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Characteristics of haemogramme were studied in 28 patients with eczema, 25 patients with neurodermatitis disseminata, 38 patients with cutaneous form of psoriasis, in whom dermatosis was manifested by extensive skin involvement. Statistical data on relative and absolute values for the groups studied confirm the rise in the numbers of monocytes, eosinophiles, lymphocytes and segmentonuclear neutrophils in the peripheral blood, this being most characteristic abnormality in the haemogramme, which was particularly noticeable in patients with clinically apparent acuity of cutaneous manifestations, universal or erythrodermic type of its affliction, lingering exacerbation state. Current knowledge about hemopoiesis and pathogenesis of the above dermatoses allow the changes being detected in the haemogramme to be considered secondary to chronic unspecific inflammation developing in the skin, being characterized, from the immunological standpoint, in a general sense, by T-cellular (tissue) immunodeficiency.

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[Pathogenesis and clinical aspects of atopic dermatitis].

Padiatr Padol

December 1990

Gottfried von Preyer'sches Kinderspital der Stadt Wien.

Atopic dermatitis (a. D.) is a chronically relapsing inflammatory disease of the skin caused by a genetically transmitted hypersensitivity to environmental substances.

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Neurodermitis disseminata may often involve the eyes. A case report is described with development of an irregular astigmatism of the cornea, which resolved spontaneously. Possibilities of transitory alteration of refraction are discussed.

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