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Collection, Fixation, and Antibody Staining of Embryos.
Cold Spring Harb Protoc
September 2024
Department of Biological Sciences, University of Arkansas, Fayetteville, Arkansas 72701, USA
The embryonic central nervous system has been used for decades as a model for understanding the genetic regulation of axon guidance and other aspects of neural development. Foundational studies using antibody staining to examine the embryonic ventral nerve cord in wild-type and mutant animals led to the discovery of evolutionarily conserved genes that regulate fundamental aspects of axon guidance, including midline crossing of axons. The development of the regular, segmentally repeating structure of axon pathways in the ventral nerve cord can illustrate basic principles of axon guidance to beginning students and can also be used by expert researchers to characterize new mutants, detect genetic interactions between known genes, and precisely quantify variations in gene function in engineered mutant lines.
View Article and Find Full Text PDFUpdates and Diagnostic Challenges in Surgical Pathology and Cytopathology.
Arch Pathol Lab Med
November 2021
The Department of Pathology, Yale School of Medicine, New Haven, Connecticut (Wang).
Examining Empathy Through Consolation Behavior in Prairie Voles.
J Undergrad Neurosci Educ
June 2021
School of Psychology and Neuroscience, University of St. Andrews, St. Andrews, UK KY16 9JP.
Empathy is an affective and cognitive event in which an organism experiences an approximation of the physical or psychological state of another organism. The phenomenon has been well-studied in humans but is not as widely researched in other animals. Burkett and colleagues in a 2016 article published in measured empathy in prairie voles () and meadow voles () by observing consolation behavior between non-stressed and stressed individuals.
View Article and Find Full Text PDFLet us not forget about our past contributions to the field of prostatic neoplasms: To some extent what we value now was already there.
Pathol Res Pract
March 2021
Institute of Pathology, Medical University Innsbruck, Innsbruck, Austria.
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